ArticleMagnetic resonance in medicine2026
Automated Coregistered Segmentation for Volumetric Analysis of Multiparametric Renal MRI.
Article in Magnetic resonance in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
purposeThis study aims to develop and evaluate a fully automated deep learning-driven postprocessing pipeline for multiparametric renal MRI, enabling accurate kidney alignment, segmentation, and quantitative feature extraction within a single efficient workflow.
methodsOur method has three main stages. First, a segmentation network delineates renal structures in high-contrast images. Next, a deep learning-based pairwise image registration algorithm maps the multiparametric image series to a common target and transfers the predicted annotations between the multiparametric images. Finally, clinically relevant quantitative parameters are extracted through region-specific assessment of renal structure and function based on the aligned and segmented multiparametric data. We used five-fold cross-validation to compare the segmentation outcomes and extracted features with manual analyses in 24 patients with prostate cancer or neuroendocrine tumors and 10 healthy subjects, each undergoing repeated scans.
resultsOur automated pipeline achieved high agreement with expert kidney segmentation while delivering significant alignment improvements through registration. Volumetric analysis showed a strong correlation (r
conclusionThe study establishes a reliable automated pipeline for renal multiparametric MRI postprocessing. The achieved accuracy and efficiency can support improved diagnosis and treatment planning for patients with kidney disease.
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