Evidence map›Paper›PMID 41639750›Full record

ReviewOne health outlook2026

Strengthening health systems in lower-middle-income countries (LMICs) in Africa through the WHO Hub for emergency preparedness and outbreak response.

Stanley Chinedu Eneh, Levi Tuwleh, Francisca Ogochukwu Onukansi, Goodness Chiburoma Anyike, Ikenna Ogini, Joseph Oladipupo, Dominic Miller, Abubakar Nazir, Ogechi Vinaprisca Ikhuoria, Collins Chibueze Anokwuru and 3 more

Abstract readReview
In one paragraph

Review in One health outlook, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Stanley Chinedu EnehYouth in Research Hub (YiRH), Enugu, Enugu State, Nigeria. Stanleyeneh234@gmail.com.ORCID http://orcid.org/0000-0002-1643-5995
Levi TuwlehCommunity Health Department, Faculty of Clinical Sciences, Obafemi Awolowo University, Osun State, Ile-Ife, Nigeria.ORCID http://orcid.org/0000-0001-5343-9840
Francisca Ogochukwu OnukansiYouth in Research Hub (YiRH), Enugu, Enugu State, Nigeria.ORCID http://orcid.org/0000-0001-9262-1135
Goodness Chiburoma AnyikeCollege of Medicine, University of Lagos, Idi-Araba, Lagos, Nigeria.
Ikenna OginiDepartment of Public Health, Federal University of Sciences and Technology, Owerri, Imo Nigeria, Nigeria.ORCID http://orcid.org/0000-0001-7271-4561
Joseph OladipupoCommunity Health Department, Faculty of Clinical Sciences, Obafemi Awolowo University, Osun State, Ile-Ife, Nigeria.
Dominic MillerEnvironmental Sciences Department, University of Cape Coast, Cape Coast, Ghana.
Abubakar NazirDepartment of Medicine, King Edward Medical University, Lahore, Pakistan.ORCID http://orcid.org/0000-0002-6650-6982
Ogechi Vinaprisca IkhuoriaYouth in Research Hub (YiRH), Enugu, Enugu State, Nigeria.ORCID http://orcid.org/0009-0005-5771-4981
Collins Chibueze AnokwuruYouth in Research Hub (YiRH), Enugu, Enugu State, Nigeria.ORCID http://orcid.org/0000-0003-2594-7009
Chidera Gabriel ObiYouth in Research Hub (YiRH), Enugu, Enugu State, Nigeria.ORCID http://orcid.org/0000-0003-3389-6176
Temitope Olumuyiwa OjoCommunity Health Department, Faculty of Clinical Sciences, Obafemi Awolowo University, Osun State, Ile-Ife, Nigeria.ORCID http://orcid.org/0000-0003-1899-5213
Yok-Fong PaatDepartment of Social Work, The University of Texas at El Paso, 500 W. University Ave, El Paso, TX, 79968, USA.ORCID http://orcid.org/0000-0001-5791-0791

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Emerging and re-emerging infectious diseases continue to pose significant threats to lower-middle-income countries (LMICs), particularly in Africa, where health systems are often resource-constrained and prone to disruptions. Drivers such as climate change, antimicrobial resistance, urbanization, civil war, poverty, globalization of travel, and high population mobility exacerbate outbreak risk and severity. This paper outlines how LMICs can strengthen health system resilience and respond more effectively to such threats by adopting practical tools and frameworks offered by the WHO Hub for Emergency Preparedness and Pandemic and Epidemic Intelligence. Key initiatives, including Epidemic Intelligence from Open Sources (EIOS), the International Pathogen Surveillance Network (IPSN), and Public Health Intelligence (PHI) capacity-building, support early detection, genomic surveillance, and data-driven decision-making. We highlight practical strategies for LMICs, including integration of Hub outputs into national policy, sustainable financing, workforce development, institutional strengthening, regional collaboration, and monitoring and evaluation. While challenges such as infrastructure gaps, data governance, and reliance on external funding remain, the WHO Hub provides a structured pathway for LMICs to enhance outbreak preparedness, reduce response times, and mitigate the impact of future epidemics.

Identifiers

PMID41639750
PMCPMC12903208

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.