Evidence map›Paper›PMID 41639661›Full record

ArticleBMC public health2026

Association between malnutrition and all-cause and cardiovascular mortality in Chinese adults with hypertension: a prospective cohort study.

Chao Yu, Lingjuan Zhu, Fang Xiong, Tao Wang, Wei Zhou, Huihui Bao, Xiaoshu Cheng

Abstract read
In one paragraph

Article in BMC public health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Chao YuDepartment of Cardiovascular Medicine, Center for Prevention and Treatment of Cardiovascular Diseases, Jiangxi Provincial Cardiovascular Disease Clinical Medical Research Center, The Second Affiliated Hospital, School of Public Health, Jiangxi Provincial Key Laboratory of Disease Prevention and Public Health, Jiangxi Medical College, Nanchang University, Nanchang, Jiangxi, China.
Lingjuan ZhuDepartment of Cardiovascular Medicine, Center for Prevention and Treatment of Cardiovascular Diseases, Jiangxi Provincial Cardiovascular Disease Clinical Medical Research Center, The Second Affiliated Hospital, School of Public Health, Jiangxi Provincial Key Laboratory of Disease Prevention and Public Health, Jiangxi Medical College, Nanchang University, Nanchang, Jiangxi, China.
Fang XiongDepartment of Nursing, The Second Affiliated Hospital of Nanchang University, Nanchang, China.
Tao WangDepartment of Cardiovascular Medicine, Center for Prevention and Treatment of Cardiovascular Diseases, Jiangxi Provincial Cardiovascular Disease Clinical Medical Research Center, The Second Affiliated Hospital, School of Public Health, Jiangxi Provincial Key Laboratory of Disease Prevention and Public Health, Jiangxi Medical College, Nanchang University, Nanchang, Jiangxi, China.
Wei ZhouDepartment of Cardiovascular Medicine, Center for Prevention and Treatment of Cardiovascular Diseases, Jiangxi Provincial Cardiovascular Disease Clinical Medical Research Center, The Second Affiliated Hospital, School of Public Health, Jiangxi Provincial Key Laboratory of Disease Prevention and Public Health, Jiangxi Medical College, Nanchang University, Nanchang, Jiangxi, China. z-w677@163.com.
Huihui BaoDepartment of Cardiovascular Medicine, Center for Prevention and Treatment of Cardiovascular Diseases, Jiangxi Provincial Cardiovascular Disease Clinical Medical Research Center, The Second Affiliated Hospital, School of Public Health, Jiangxi Provincial Key Laboratory of Disease Prevention and Public Health, Jiangxi Medical College, Nanchang University, Nanchang, Jiangxi, China.
Xiaoshu ChengDepartment of Cardiovascular Medicine, Center for Prevention and Treatment of Cardiovascular Diseases, Jiangxi Provincial Cardiovascular Disease Clinical Medical Research Center, The Second Affiliated Hospital, School of Public Health, Jiangxi Provincial Key Laboratory of Disease Prevention and Public Health, Jiangxi Medical College, Nanchang University, Nanchang, Jiangxi, China.

Funding

Cultivation of backup projects for National Science and Technology Awards 20223AEI91007Science Fund for Distinguished Young Scholars of Jiangxi Province 20212ACB206019, 20224BAB206090, 20232BAB206140, and 20232ACB216006
6 · The paper itself

Abstract

objectiveThere is a paucity of data regarding the association between malnutrition and mortality in China. This study aimed to explore the association between the geriatric nutritional risk index (GNRI) and all-cause and cardiovascular mortality in Chinese adults with hypertension.

methodsA total of 14,221 participants with hypertension (mean age, 63.8 ± 9.4 years; 47.2% males) were included in a prospective cohort analysis. GNRI was calculated using the following formula: [1.489 × serum albumin (g/L)]﹢[41.7 × (actual weight/ideal weight)]. The primary outcomes of this study were all-cause and cardiovascular mortalities. Cox regression analysis, restricted cubic spline analysis, and Kaplan-Meier curves were used to evaluate the association between GNRI and mortality.

resultsOver a mean follow-up of 3.9 years, 805 deaths were recorded, of which 397 were due to cardiovascular disease. Overall, GNRI was significantly negatively associated with all-cause and cardiovascular mortality. Compared with participants with normal nutritional status, the hazard ratios for all-cause and cardiovascular mortality were 1.78 (95% CI: 1.41-2.24) and 1.66 (95% CI: 1.17-2.33) among those with mild malnutrition, and 2.13 (95% CI: 1.46-3.11) and 2.38 (95% CI: 1.41-4.02) among those with moderate-to-severe malnutrition, respectively. The association between GNRI and all-cause (P for interaction = 0.004) and cardiovascular mortality (P for interaction = 0.002) was stronger in non-overweight individuals (body mass index (BMI) < 24 kg/m2) than in those who were overweight (BMI ≥ 24 kg/m2).

conclusionMalnutrition independently increases the risk of all-cause and cardiovascular mortality in individuals with hypertension.

Indexed as

Cardiovascular DiseasesHypertensionMalnutritionAgedCause of DeathChinaEast Asian PeopleFemaleGeriatric AssessmentHumansMaleMiddle AgedNutrition AssessmentProspective StudiesRisk FactorsAll-cause mortalityCardiovascular mortalityGeriatric nutritional risk index (GNRI)Hypertension

Identifiers

PMID41639661
PMCPMC12964918

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.