Evidence map›Paper›PMID 41639623›Full record

ArticleBMC cardiovascular disorders2026

Comparative analysis of Chinese large language model performance on atrial fibrillation questions.

Guijian Liu, Kuan Cheng, Ye Xu, Yang Pang, Yunlong Ling, Qingxing Chen, Wenqing Zhu, Junbo Ge

Abstract readComparative Study
In one paragraph

Article in BMC cardiovascular disorders, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Guijian Liu *Department of Cardiology, Zhongshan Hospital, Shanghai Institute of Cardiovascular Diseases, Fudan University, China National Clinical Research Center for Interventional Medicine, No.180, Fenglin Road, Shanghai, 200032, China.
Kuan Cheng *Department of Cardiology, Zhongshan Hospital, Shanghai Institute of Cardiovascular Diseases, Fudan University, China National Clinical Research Center for Interventional Medicine, No.180, Fenglin Road, Shanghai, 200032, China.
Ye XuDepartment of Cardiology, Zhongshan Hospital, Shanghai Institute of Cardiovascular Diseases, Fudan University, China National Clinical Research Center for Interventional Medicine, No.180, Fenglin Road, Shanghai, 200032, China.
Yang PangDepartment of Cardiology, Zhongshan Hospital, Shanghai Institute of Cardiovascular Diseases, Fudan University, China National Clinical Research Center for Interventional Medicine, No.180, Fenglin Road, Shanghai, 200032, China.
Yunlong LingDepartment of Cardiology, Zhongshan Hospital, Shanghai Institute of Cardiovascular Diseases, Fudan University, China National Clinical Research Center for Interventional Medicine, No.180, Fenglin Road, Shanghai, 200032, China.
Qingxing ChenDepartment of Cardiology, Zhongshan Hospital, Shanghai Institute of Cardiovascular Diseases, Fudan University, China National Clinical Research Center for Interventional Medicine, No.180, Fenglin Road, Shanghai, 200032, China. chen.qingxing@zs-hospital.sh.cn.
Wenqing ZhuDepartment of Cardiology, Zhongshan Hospital, Shanghai Institute of Cardiovascular Diseases, Fudan University, China National Clinical Research Center for Interventional Medicine, No.180, Fenglin Road, Shanghai, 200032, China. zhu.wenqing@zs-hospital.sh.cn.
Junbo GeDepartment of Cardiology, Zhongshan Hospital, Shanghai Institute of Cardiovascular Diseases, Fudan University, China National Clinical Research Center for Interventional Medicine, No.180, Fenglin Road, Shanghai, 200032, China.

Funding

Shanghai Top Priority research center construction project 2022ZZ01010
6 · The paper itself

Abstract

backgroundThe first seven Chinese Large language models (LLMs) were launched to the public on August 31st,2023.However, the extent to which Chinese LLMs can assist atrial fibrillation༈AF༉patients remains unknown. We sought to assess the Chinese LLMs performance of providing responses to AF patient questions.

methodThis cross-sectional study compared seven Chinese LLM chatbots including ABAB, Baichuan, Chatglm, Doubao, Ernie bot, Sensechat and ZidongTaichu. First, cardiologists compiled a list of frequently asked questions by patients with AF. Responses from LLMs were collected. We developed a scoring system known as SCECCE, which consists of 6 aspects including safety, correctness, error, completeness, conciseness and elaboration. Each response was assessed by an expert committee according to SCECCE scoring system.

resultA total of 231 responses were obtained. Overall, the median SCECCE score was 10[IQR, 7–10] with a mean(SD) score of 8.6(2.0). No significant statistical differences were observed in SCECCE scores among seven LLMs(p = 0.08). The maximum total SCECCE score was 330 points. Ernie bot attained the highest total score of 299 points. Doubao provided safe responses to 97% of the questions. In terms of correctness and error, the overall comparison of each group showed no statistically significant difference. Ernie bot exhibited the best performance with an accuracy rate of 87.9%.

conclusionOur findings from this preliminary study suggested that certain Chinese LLMs could generate accurate and comprehensive answers to specific patient questions on atrial fibrillation. Nevertheless, this performance does not warrant clinical application, with safety being a foremost concern among the considerable challenges that lie ahead.

Indexed as

Atrial FibrillationLarge Language ModelsChinaCross-Sectional StudiesEast Asian PeopleFemaleHumansMaleSurveys and QuestionnairesAccuracyArtificial intelligenceAtrial fibrillationLarge language modelSafety

Identifiers

PMID41639623
PMCPMC12958689

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.