Evidence map›Paper›PMID 41639589›Full record

ArticleNature communications2026

Mutation in HER1 enhances stigma exsertion and hybrid seed production in rice.

Daiming Guo, Kangxi Du, Peizhou Xu, Su Liu, Mengyuan Li, Jiazhi Dong, Jingcheng Zhao, Mingming Zhang, Gege Zhou, Yong Li and 13 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nature communications, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors.

Daiming Guo *Rice Research Institute, Sichuan Agricultural University, Chengdu, Sichuan, China.ORCID 0000-0002-8107-8453
Kangxi Du *Rice Research Institute, Sichuan Agricultural University, Chengdu, Sichuan, China.ORCID 0000-0002-7985-7861
Peizhou Xu *Rice Research Institute, Sichuan Agricultural University, Chengdu, Sichuan, China.
Su LiuRice Research Institute, Sichuan Agricultural University, Chengdu, Sichuan, China.
Mengyuan LiRice Research Institute, Sichuan Agricultural University, Chengdu, Sichuan, China.
Jiazhi DongRice Research Institute, Sichuan Agricultural University, Chengdu, Sichuan, China.
Jingcheng ZhaoRice Research Institute, Sichuan Agricultural University, Chengdu, Sichuan, China.
Mingming ZhangRice Research Institute, Sichuan Agricultural University, Chengdu, Sichuan, China.
Gege ZhouRice Research Institute, Sichuan Agricultural University, Chengdu, Sichuan, China.
Yong LiRice Research Institute, Sichuan Agricultural University, Chengdu, Sichuan, China.
Xinmiao YuanRice Research Institute, Sichuan Agricultural University, Chengdu, Sichuan, China.
Fangli JinRice Research Institute, Sichuan Agricultural University, Chengdu, Sichuan, China.
Zhixue ZhaoState Key Laboratory of Crop Gene Exploration and Utilization in Southwest China, Chengdu, Sichuan, China.
Shicong YuRice Research Institute, Sichuan Agricultural University, Chengdu, Sichuan, China.
Duo XiaRice Research Institute, Sichuan Agricultural University, Chengdu, Sichuan, China.
Hongyu ZhangRice Research Institute, Sichuan Agricultural University, Chengdu, Sichuan, China.
Xiaoqiong ChenRice Research Institute, Sichuan Agricultural University, Chengdu, Sichuan, China.
Ming LuoCSIRO Agriculture and Food, Canberra, Australia.ORCID 0000-0002-8816-3183
Asif AliRice Research Institute, Sichuan Agricultural University, Chengdu, Sichuan, China.ORCID 0000-0001-7688-148X
Yunfeng TianRice Research Institute, Sichuan Agricultural University, Chengdu, Sichuan, China.
Hao ZhouRice Research Institute, Sichuan Agricultural University, Chengdu, Sichuan, China. zhouhao666@foxmail.com.ORCID 0000-0003-4803-4990
Xianjun WuRice Research Institute, Sichuan Agricultural University, Chengdu, Sichuan, China. wuxj@sicau.edu.cn.ORCID 0000-0003-0157-0235
Yongxiang LiaoRice Research Institute, Sichuan Agricultural University, Chengdu, Sichuan, China. liaoyongxiang123@163.com.ORCID 0000-0001-8973-1974

Funding

Department of Science and Technology of Sichuan Province (Sichuan Provincial Department of Science and Technology) 2023NSFSC0013Department of Science and Technology of Sichuan Province (Sichuan Provincial Department of Science and Technology) 2024ZYD0007National Natural Science Foundation of China (National Science Foundation of China) 32372081
6 · The paper itself

Abstract

Hybrid rice has achieved a significant leap in rice yield, but the low outcrossing rate of sterile lines limits hybrid seed production due to rice's self-pollinating habits, constraining the further development and widespread adoption of hybrid rice. Stigma exsertion is a critical trait affecting outcrossing rate. Here we characterize a rice mutant, high exsertion rate1 (her1), characterized by enlarged stigma and enhanced stigma exsertion. HER1 encodes a SET domain-containing protein that binds to histone H3 at methylated lysine 9 and regulates H3K9me2 levels. Loss of function of HER1 results in reduced H3K9me2 levels in her1, increasing the transcription of Downstream2 (DS2), which positively controls stigma size. Using the loss-of-function allele of her1, we develop a high-exsertion male-sterile line herA, which increases hybrid seed production by more than 20% in field conditions, substantiating the breeding value of HER1 in hybrid seed production.

Indexed as

FlowersMutationOryzaPlant ProteinsSeedsAllelesGene Expression Regulation, PlantHistonesPlants, Genetically ModifiedHistonesPlant Proteins

Identifiers

PMID41639589
PMCPMC12979660

What OpenQuestion holds

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LicenceCC BY-NC-ND
Read underepoch 390

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.