Evidence map›Paper›PMID 41639528›Full record

ArticleEnvironmental science and pollution research international2026

Valorization of bone waste: effect of animal bone origin on hydroxyapatite structure and properties.

Liana Mkhitaryan, Lilit Baghdasaryan, Khachik Nazaretyan, Zhenya Khachatryan, Arevik Khachatryan, Mikayel Torosyan, Marina Aghayan, Miguel Angel Rodríguez, Viktorya Rstakyan

Abstract read
In one paragraph

Article in Environmental science and pollution research international, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Liana MkhitaryanGroup of Ceramic Biomaterials, A. B. Nalbandyan Institute of Chemical Physics, National Academy of Sciences, P. Sevak 5/2, 0014, Yerevan, Armenia.
Lilit BaghdasaryanGroup of Ceramic Biomaterials, A. B. Nalbandyan Institute of Chemical Physics, National Academy of Sciences, P. Sevak 5/2, 0014, Yerevan, Armenia.
Khachik NazaretyanLaboratory of Macrokinetics of Solid State Reactions, A. B. Nalbandyan Institute of Chemical Physics, National Academy of Sciences, P. Sevak 5/2, 0014, Yerevan, Armenia.
Zhenya KhachatryanGroup of Ceramic Biomaterials, A. B. Nalbandyan Institute of Chemical Physics, National Academy of Sciences, P. Sevak 5/2, 0014, Yerevan, Armenia.
Arevik KhachatryanGroup of Ceramic Biomaterials, A. B. Nalbandyan Institute of Chemical Physics, National Academy of Sciences, P. Sevak 5/2, 0014, Yerevan, Armenia.
Mikayel TorosyanInstitute of Pharmacy, Yerevan State University, Alek Manukyan 1, 0025, Yerevan, Armenia.
Marina Aghayan3D Printing Research Laboratory, A. B. Nalbandyan Institute of Chemical Physics, National Academy of Sciences, P. Sevak 5/2, 0014, Yerevan, Armenia.
Miguel Angel RodríguezDepartment of Ceramics, Institute of Ceramics and Glass, C/ Kelsen 5, 28049 , Madrid, Spain.
Viktorya RstakyanGroup of Ceramic Biomaterials, A. B. Nalbandyan Institute of Chemical Physics, National Academy of Sciences, P. Sevak 5/2, 0014, Yerevan, Armenia. vrstakyan@ichph.sci.am.ORCID http://orcid.org/0009-0002-8640-0584

Funding

Higher Education and Science Committee Ministry of Education, Science, Culture and Sport RA 22rl-050
6 · The paper itself

Abstract

This study demonstrates the valorization of bone waste from different animal sources as a sustainable approach to produce high-value hydroxyapatite (HA) powders, supporting circular economy principles. The findings provide a scientific basis for selecting bone waste sources depending on desired material properties, promoting resource-efficient recovery and reuse of biowaste. Three different types of bone-bovine, ostrich, and porcine-were selected for this research to compare species-dependent differences in HA derived from animal sources. Bovine bone served as a common reference, ostrich bone represented a non-mammalian source, and porcine bone was chosen for its close structural similarity to human bone. The HA powders were characterized in terms of particle size, specific surface area, crystallite size, phase composition, and porosity. X-ray diffraction (XRD) analysis revealed variations in crystallite size with calcination temperature. Mechanical testing revealed that bovine-derived HA exhibited the highest compressive strength (17 MPa) and porcine-derived HA showed the highest hardness (0.5 GPa). These findings highlight the significant influence of the bone source on the microstructural and physicochemical properties of HA, providing a foundation for selecting optimal HA sources for targeted applications. With the results obtained in this paper, it is possible to select the animal of origin of the bones to be used based on the desired characteristics of the powder to be developed.

Indexed as

Bone and BonesDurapatiteAnimalsCattleParticle SizePorosityPowdersStruthioniformesSwineX-Ray DiffractionDurapatitePowdersBiomaterialBiowaste utilizationBoneHydroxyapatiteSinterabilityWaste valorization

Identifiers

PMID41639528
PMCPMC12982306

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.