Evidence map›Paper›PMID 41639520›Full record

ArticleJournal of cardiovascular translational research2026

Pulmonary Artery Banding: an Effective in-vivo Acute Model of Functional Tricuspid Regurgitation for Transcatheter Interventions.

Guido Ascione, Stefano Stella, Alessandro Addis, Nina Ajmone Marsan, Hadewych Van Hauwermeiren, Juan F Granada, Guido Gelpi, Paolo Denti

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Article in Journal of cardiovascular translational research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Guido AscioneDepartment of Cardiac Surgery, Heart Valve Center, IRCCS San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Via Olgettina 60, 20132, Milan, Italy. guidoascione@gmail.com.ORCID 0000-0002-7727-0573
Stefano StellaEchocardiography Laboratory, Heart Valve Center, IRCCS San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan, Italy.
Alessandro AddisCRABCC, Biotechnology Research Center for Cardiothoracic Applications, Rivolta D'Adda, Italy.
Nina Ajmone MarsanDepartment of Cardiology, Leiden University Medical Center, Leiden, Netherlands.
Hadewych Van HauwermeirenMedanex Clinic (NAMSA), Diest, Belgium.
Juan F GranadaCardiovascular Research Foundation, New York, NY, USA.
Guido GelpiCardiac Surgery Department, Fondazione IRCCS Ca' Granda - Ospedale Maggiore Policlinico, Milan, Italy.
Paolo DentiDepartment of Cardiac Surgery, Heart Valve Center, IRCCS San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Via Olgettina 60, 20132, Milan, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tricuspid regurgitation (TR) is a highly morbid and often untreated valvular heart disease. New devices are under development to address this unmet need, necessitating valid models to test their efficacy. Aim of this study was to assess feasibility and reliability of pulmonary artery banding (PAB) as a pathological acute model of functional TR. Eight pigs underwent right thoracotomy, with an umbilical tape placed around the main pulmonary trunk, followed by controlled reduction of the pulmonary artery lumen via a tourniquet system. No animals died during the procedure. After PAB, right ventricular (RV) mean pressure, RV basal and mid-diameter and tricuspid septo-lateral diameter significantly increased (+ 97%, + 23%, + 32%, + 20%, p < 0.01 for all). Consequently, TR was at least moderate-to-severe in all the animals and these modifications remained stable for up to one hour. PAB therefore represents a reliable, one-step model of functional TR ideal to test the efficacy of new tricuspid devices.

Indexed as

Cardiac CatheterizationHeart Valve Prosthesis ImplantationPulmonary ArteryTricuspid ValveTricuspid Valve InsufficiencyAcute DiseaseAnimalsDisease Models, AnimalFeasibility StudiesFemaleSeverity of Illness IndexSus scrofaSwineTime FactorsVentricular Function, RightLarge animal modelPulmonary artery bandingTranscatheter tricuspid valve interventionsTranscatheter tricuspid valve repairTranscatheter tricuspid valve replacementTricuspid regurgitation

Identifiers

PMID41639520

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.