ArticleNature2026
Efficient near-telomere-to-telomere assembly of nanopore simplex reads.
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Article in Nature, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
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34citing papers in PubMed
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Who cites it
34 citing papers in PubMed.
- De Novo Assembly of the Trypanosoma congolense Genome Reveals an Organization Influenced by Antigenic Variation but Distinct from Trypanosoma brucei.Genome biology and evolution · 2026Article
- Revisiting the genome assembly of Lupinus species reveals differential diploidization after a shared whole-genome duplication.G3 (Bethesda, Md.) · 2026Article
- Improving Long-Read Somatic Structural Variant Calling with Pangenome and De Novo Personal Genome Assembly.Cancer research communications · 2026Article
- Article
- Article
- A T2T Genome of the Lobed-Lip Iguazu Joana (Crenicichla tuca) Reveals Intrachromosomal Rearrangements and Trans-species Polymorphism in Cichlid Fishes.Genome biology and evolution · 2026Article
- Long-term surveillance reveals hybridization by nuclear reassortment and intercontinental spread as major evolutionary drivers in wheat yellow rust.The New phytologist · 2026Article
- Leveraging ONT move table values for signal aware variant calling.Bioinformatics (Oxford, England) · 2026Article
- HPRC2: A human pangenome reference with near-complete coverage of common genetic variation.bioRxiv : the preprint server for biology · 2026Article
- Personalized reference genome-based pipeline reveals comprehensive haplotype-resolved views of cancer genomes.bioRxiv : the preprint server for biology · 2026Article
- Article
- Haplotype-aware long-read error correction.Algorithms for molecular biology : AMB · 2026Article
- kmerRRR: A k-mer based tool for functional genomics in Repeat Rich Regions.bioRxiv : the preprint server for biology · 2026Article
- HOROSCOPE: Decoding human centromere architecture from short reads usingbioRxiv : the preprint server for biology · 2026Article
- The first chromosome-scale genome assembly for Dermacentor reticulatus: a key vector of tick-borne pathogens of public and veterinary health importance in Europe.BMC biology · 2026Article
- Genome sequence ofMicrobiology resource announcements · 2026Article
- Two melanic pigment patterns are associated with a sex chromosome-linked oncogene in the mountain swordtailbioRxiv : the preprint server for biology · 2026Article
- An improved Solanum verrucosum genome provides insight into potato centromeres and epigenetic regulation.G3 (Bethesda, Md.) · 2026Article
- Nanopore Data-Driven Near-T2T Genome Assembly ofPlants (Basel, Switzerland) · 2026Article
- Determinants of haplotype phasing accuracy in long-read human genome sequencing.bioRxiv : the preprint server for biology · 2026Article
Corrections and comments
- Update of
Authors and funding
8 authors.
Haoyu Cheng *Department of Biomedical Informatics and Data Science, Yale School of Medicine, New Haven, CT, USA. haoyu.cheng@yale.edu.ORCID http://orcid.org/0000-0002-9209-5793
Han Qu *Department of Biomedical Informatics, Harvard Medical School, Boston, MA, USA.ORCID http://orcid.org/0000-0002-6016-5152
Sean McKenzieOxford Nanopore Technologies, Oxford, UK.
Katherine R LawrenceOxford Nanopore Technologies, Oxford, UK.
Rhydian WindsorOxford Nanopore Technologies, Oxford, UK.
Mike VellaOxford Nanopore Technologies, Oxford, UK.
Peter J ParkDepartment of Biomedical Informatics, Harvard Medical School, Boston, MA, USA.ORCID http://orcid.org/0000-0001-9378-960X
Heng LiDepartment of Biomedical Informatics, Harvard Medical School, Boston, MA, USA. hli@ds.dfci.harvard.edu.ORCID http://orcid.org/0000-0003-4874-2874
Funding
The WashU-UCSC-EBI Human Genome Reference Center."U41HG010972 · NHGRI · WASHINGTON UNIVERSITY · PI Ira M Hall, Heng Li · 2019 to 2026
$24.9MELSI Administrative Supplement - Center for Human Reference Genome DiversityU01HG010971 · NHGRI · UNIVERSITY OF CALIFORNIA SANTA CRUZ · PI EICHLER, EVAN, JARVIS, ERICH D · 2019 to 2023
$18.4MGenetic & Social Determinants of Health: Center for Admixture Science and TechnologyRM1HG011558 · NHGRI · YALE UNIVERSITY · PI FRAZER, KELLY A, GYMREK, MELISSA · 2021 to 2025
$11.2MData Analysis Center for Somatic Mosaicism Across Human Tissues NetworkUM1DA058230 · NIDA · HARVARD MEDICAL SCHOOL · PI Peter J Park · 2023 to 2026
$6.3MAdvanced computational methods in analyzing high-throughput sequencing dataR01HG010040 · NHGRI · DANA-FARBER CANCER INST · PI Heng Li · 2018 to 2026
$3.7MEnhancement and further development of informatics methods for long-read cancer sequencingU24CA294203 · NCI · DANA-FARBER CANCER INST · PI Catarina D. Campbell, Heng Li · 2024 to 2026
$2.6MMutational signature analysis: methods and applications to the clinicR01CA269805 · NCI · HARVARD MEDICAL SCHOOL · PI Peter J Park · 2022 to 2026
$2.2MCalling germline and mosaic variants from long genomic and RNA-seq readsR01HG014175 · NHGRI · DANA-FARBER CANCER INST · PI Heng Li · 2025 to 2026
$1.0MRobust and cost-effective computational methods for haplotype-resolved genome assembliesR00HG012798 · NHGRI · YALE UNIVERSITY · PI Haoyu Cheng · 2024 to 2026
$747kRobust and cost-effective computational methods for haplotype-resolved genome assembliesK99HG012798 · NHGRI · DANA-FARBER CANCER INST · PI CHENG, HAOYU · 2023 to 2024
$165kNCI NIH HHS R01 CA269805NCI NIH HHS U24 CA294203NHGRI NIH HHS K99 HG012798NHGRI NIH HHS R00 HG012798NHGRI NIH HHS R01 HG010040NHGRI NIH HHS R01 HG014175NHGRI NIH HHS RM1 HG011558NHGRI NIH HHS U01 HG010971NHGRI NIH HHS U41 HG010972NIDA NIH HHS UM1 DA058230
Abstract
Telomere-to-telomere (T2T) assembly is the ultimate goal for de novo genome assembly. Existing algorithms
Indexed as
Nanopore SequencingSequence Analysis, DNATelomereAlgorithmsAnimalsHumans
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.