Evidence map›Paper›PMID 41639244›Full record

ArticleScientific reports2026

Time-of-day differences in daily functioning in children with obsessive-compulsive disorder.

Masahide Usami, Yoshinori Sasaki, Mayuna Ichikawa, Miki Matsudo, Ayaka Hashimoto, Shun Kusanish, Nobutada Kato, Ryuwa Makiyama, Mutsumi Ohashi, Yui Higashino and 18 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

28 authors.

Masahide UsamiDepartment of Child and Adolescent Psychiatry, National Kohnodai Medical Center, Japan Institute for Health Security, 1-7-1 Kohnodai, Ichikawa, 272-8516, Chiba, Japan. usami.m@jihs.go.jp.
Yoshinori SasakiDepartment of Psychiatry and Behavioral Science, Institute of Science Tokyo, Tokyo, Japan.
Mayuna IchikawaDepartment of Clinical Psychology, National Kohnodai Medical Center, Japan Institute for Health Security, Ichikawa, Japan.
Miki MatsudoDepartment of Clinical Psychology, National Kohnodai Medical Center, Japan Institute for Health Security, Ichikawa, Japan.
Ayaka HashimotoDepartment of Clinical Psychology, National Kohnodai Medical Center, Japan Institute for Health Security, Ichikawa, Japan.
Shun KusanishDepartment of Child and Adolescent Psychiatry, National Kohnodai Medical Center, Japan Institute for Health Security, 1-7-1 Kohnodai, Ichikawa, 272-8516, Chiba, Japan.
Nobutada KatoDepartment of Child and Adolescent Psychiatry, National Kohnodai Medical Center, Japan Institute for Health Security, 1-7-1 Kohnodai, Ichikawa, 272-8516, Chiba, Japan.
Ryuwa MakiyamaDepartment of Child and Adolescent Psychiatry, National Kohnodai Medical Center, Japan Institute for Health Security, 1-7-1 Kohnodai, Ichikawa, 272-8516, Chiba, Japan.
Mutsumi OhashiDepartment of Child and Adolescent Psychiatry, National Kohnodai Medical Center, Japan Institute for Health Security, 1-7-1 Kohnodai, Ichikawa, 272-8516, Chiba, Japan.
Yui HigashinoDepartment of Child and Adolescent Psychiatry, National Kohnodai Medical Center, Japan Institute for Health Security, 1-7-1 Kohnodai, Ichikawa, 272-8516, Chiba, Japan.
Yusuke KonoDepartment of Child and Adolescent Psychiatry, National Kohnodai Medical Center, Japan Institute for Health Security, 1-7-1 Kohnodai, Ichikawa, 272-8516, Chiba, Japan.
Haruna MatsudoDepartment of Child and Adolescent Psychiatry, National Kohnodai Medical Center, Japan Institute for Health Security, 1-7-1 Kohnodai, Ichikawa, 272-8516, Chiba, Japan.
Minjae MaDepartment of Child and Adolescent Psychiatry, National Kohnodai Medical Center, Japan Institute for Health Security, 1-7-1 Kohnodai, Ichikawa, 272-8516, Chiba, Japan.
Yuuki SakohDepartment of Child and Adolescent Psychiatry, National Kohnodai Medical Center, Japan Institute for Health Security, 1-7-1 Kohnodai, Ichikawa, 272-8516, Chiba, Japan.
Maiko OdakaDepartment of Child and Adolescent Psychiatry, National Kohnodai Medical Center, Japan Institute for Health Security, 1-7-1 Kohnodai, Ichikawa, 272-8516, Chiba, Japan.
Kotoe ItagakiDepartment of Clinical Psychology, National Kohnodai Medical Center, Japan Institute for Health Security, Ichikawa, Japan.
Keita YamamotoDepartment of Social Work, National Kohnodai Medical Center, Japan Institute for Health Security, Ichikawa, Japan.
Momoka TakahashiDepartment of Social Work, National Kohnodai Medical Center, Japan Institute for Health Security, Ichikawa, Japan.
Yuta YoshimuraDepartment of Psychiatry, Fukuoka University, Fukuoka, Japan.
Saori InoueDepartment of Child Psychiatry, Ehime University Graduate School of Medicine, Toon City, Japan.
Masahiro IshidaDepartment of Psychiatry, Fukuoka University, Fukuoka, Japan.
Masaya ItoNational Center for Cognitive Behavior Therapy and Research, National Center of Neurology and Psychiatry, Kodaira, Japan.
Katsunaka MikamiDepartment of Psychiatry, Tokai University School of Medicine, Kanagawa, Japan.
Noa TsujiiDepartment of Child Mental Health and Development, Toyama University Hospital, Toyama, Japan.
Hiroaki KiharaDepartment of Neuropsychiatry, Kanazawa Medical University, Ishikawa, Japan.
Kumi InazakiDepartment of Child and Adolescent Psychiatry, National Kohnodai Medical Center, Japan Institute for Health Security, 1-7-1 Kohnodai, Ichikawa, 272-8516, Chiba, Japan.
Yuki HakoshimaDepartment of Child and Adolescent Psychiatry, National Kohnodai Medical Center, Japan Institute for Health Security, 1-7-1 Kohnodai, Ichikawa, 272-8516, Chiba, Japan.
Yuki MizumotoDepartment of Child and Adolescent Psychiatry, National Kohnodai Medical Center, Japan Institute for Health Security, 1-7-1 Kohnodai, Ichikawa, 272-8516, Chiba, Japan.

Funding

Japan Institute for Health Security 24A1014the Health Labor Sciences Research Grant 23GC0013
6 · The paper itself

Abstract

This study aimed to evaluate time-of-day-specific functional impairments in children with obsessive-compulsive disorder (OCD) and identify related clinical and psychosocial factors. The registry data for a total of 136 children diagnosed with OCD was analyzed. Questionnaire - Children with Difficulties (QCD) was used to assess functional difficulties across daily lives and was reported by the parents. The QCD scores of the children with OCD were compared with community norms. Multiple regression analyses were used to examine the associations of the QCD domains with age, weekday sleep, anxiety, depression, behavioral problems, and siblings. The mean age of patients in the OCD group was 11.46 years (SD = 2.27), with 69 boys (51.1%) and 66 girls (48.9%). The children with OCD scored significantly lower across all QCD domains (all p < .01), with large effects for night (d = - 2.04), total QCD (d = - 2.10), school (d = - 1.90), and after-school (d = - 2.03) compared to the community sample. In the regression analyses, higher behavioral problem scores predicted better functioning in the morning and evening, whereas a greater number of siblings predicted poorer morning functioning. Higher anxiety scores were significantly associated with better night-time functioning. However, depressive symptoms were not significantly associated with overall functioning. Children and adolescents with OCD demonstrated marked domain-specific functional impairments, particularly during school, after school, and nighttime routines. Distinct psychosocial factors, including behavioral problems, sibling presence, and anxiety symptoms, were associated with time-specific functioning, underscoring the need for targeted, time-sensitive interventions.

Indexed as

Activities of Daily LivingObsessive-Compulsive DisorderAdolescentAnxietyChildDepressionFemaleHumansMaleSleepSurveys and QuestionnairesTime FactorsAdolescentChildFamily burdenObsessive compulsive disorder

Identifiers

PMID41639244
PMCPMC12923591

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.