Evidence map›Paper›PMID 41639229›Full record

ArticleMolecular psychiatry2026

Tetrodotoxin-resistant Na

Junlong Li, Yujie Xiao, Shuxuan Lyu, Kun Wang, Heyuan Zhang, Yuxiang Zheng, Xiaoxue Zhang, Hongkun Yang, Yousheng Shu

Abstract read
PubMed Publisher
In one paragraph

Article in Molecular psychiatry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Junlong Li *Department of Neurology, Jinshan Hospital, Institute for Translational Brain Research, State Key Laboratory of Brain Function and Disorders, MOE Frontiers Center for Brain Science, MOE Innovative Center for New Drug Development of Immune Inflammatory Diseases, Fudan University, Shanghai, 201508, China.
Yujie Xiao *Department of Neurology, Jinshan Hospital, Institute for Translational Brain Research, State Key Laboratory of Brain Function and Disorders, MOE Frontiers Center for Brain Science, MOE Innovative Center for New Drug Development of Immune Inflammatory Diseases, Fudan University, Shanghai, 201508, China.
Shuxuan Lyu *Department of Neurology, Jinshan Hospital, Institute for Translational Brain Research, State Key Laboratory of Brain Function and Disorders, MOE Frontiers Center for Brain Science, MOE Innovative Center for New Drug Development of Immune Inflammatory Diseases, Fudan University, Shanghai, 201508, China.ORCID http://orcid.org/0000-0002-4196-5461
Kun WangDepartment of Neurology, Jinshan Hospital, Institute for Translational Brain Research, State Key Laboratory of Brain Function and Disorders, MOE Frontiers Center for Brain Science, MOE Innovative Center for New Drug Development of Immune Inflammatory Diseases, Fudan University, Shanghai, 201508, China.
Heyuan ZhangDepartment of Neurology, Jinshan Hospital, Institute for Translational Brain Research, State Key Laboratory of Brain Function and Disorders, MOE Frontiers Center for Brain Science, MOE Innovative Center for New Drug Development of Immune Inflammatory Diseases, Fudan University, Shanghai, 201508, China.
Yuxiang ZhengDepartment of Neurology, Jinshan Hospital, Institute for Translational Brain Research, State Key Laboratory of Brain Function and Disorders, MOE Frontiers Center for Brain Science, MOE Innovative Center for New Drug Development of Immune Inflammatory Diseases, Fudan University, Shanghai, 201508, China.ORCID http://orcid.org/0009-0001-8680-2682
Xiaoxue ZhangDepartment of Neurology, Jinshan Hospital, Institute for Translational Brain Research, State Key Laboratory of Brain Function and Disorders, MOE Frontiers Center for Brain Science, MOE Innovative Center for New Drug Development of Immune Inflammatory Diseases, Fudan University, Shanghai, 201508, China.
Hongkun YangDepartment of Neurology, Jinshan Hospital, Institute for Translational Brain Research, State Key Laboratory of Brain Function and Disorders, MOE Frontiers Center for Brain Science, MOE Innovative Center for New Drug Development of Immune Inflammatory Diseases, Fudan University, Shanghai, 201508, China.
Yousheng ShuDepartment of Neurology, Jinshan Hospital, Institute for Translational Brain Research, State Key Laboratory of Brain Function and Disorders, MOE Frontiers Center for Brain Science, MOE Innovative Center for New Drug Development of Immune Inflammatory Diseases, Fudan University, Shanghai, 201508, China. yousheng@fudan.edu.cn.ORCID http://orcid.org/0000-0002-2834-2876

Funding

China Postdoctoral Science Foundation 2022M720801China Postdoctoral Science Foundation 2023M740657Ministry of Science and Technology of the People's Republic of China (Chinese Ministry of Science and Technology) 2021ZD0202500National Natural Science Foundation of China (National Science Foundation of China) 32130044National Natural Science Foundation of China (National Science Foundation of China) 32500857National Natural Science Foundation of China (National Science Foundation of China) T2241002
6 · The paper itself

Abstract

Lateral septum (LS) plays crucial roles in regulating various emotional behaviors. The molecular mechanism governing the excitability of LS neuron (LSN) remains unclear. Using single-nucleus RNA sequencing (snRNA-seq) and immunostaining, we detected high expression levels of Scn5a, the cardiac TTX-resistant voltage-gated Na

Indexed as

NAV1.5 Voltage-Gated Sodium ChannelAction PotentialsAnimalsAnxietyDepressionEmotionsFlecainideMaleMembrane PotentialsMiceMice, Inbred C57BLMice, KnockoutNeuronsSeptal NucleiStress, PsychologicalTetrodotoxinFlecainideNAV1.5 Voltage-Gated Sodium ChannelScn5a protein, mouseTetrodotoxin

Identifiers

PMID41639229

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.