Evidence map›Paper›PMID 41639212›Full record

ArticleScientific reports2026

The weight-adjusted waist index predicts sarcopenia in community-dwelling older adults in a nationwide multicenter prospective study.

Kyu-Ho Lee, Soon Young Hwang, Ji Hye Heo, Jun Goo Kang, Miji Kim, Chang Won Won, Kyung Mook Choi, Eun Roh

Abstract readMulticenter Study
In one paragraph

Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Kyu-Ho LeeDepartment of Internal Medicine, Hallym University Sacred Heart Hospital, Hallym University College of Medicine, Anyang, 14068, Republic of Korea.
Soon Young HwangDepartment of Biostatistics, Korea University College of Medicine, Seoul, 02841, Republic of Korea.
Ji Hye HeoDepartment of Internal Medicine, Hallym University Sacred Heart Hospital, Hallym University College of Medicine, Anyang, 14068, Republic of Korea.
Jun Goo KangDepartment of Internal Medicine, Hallym University Sacred Heart Hospital, Hallym University College of Medicine, Anyang, 14068, Republic of Korea.
Miji KimDepartment of Health Sciences and Technology, Kyung Hee University College of Medicine, Seoul, 02447, Republic of Korea.
Chang Won WonElderly Frailty Research Center, Department of Family Medicine, Kyung Hee University College of Medicine, Kyung Hee Medical Center, Seoul, 02447, Republic of Korea.
Kyung Mook ChoiDepartment of Internal Medicine, Korea University Guro Hospital, Korea University College of Medicine, Seoul, 08308, Republic of Korea.
Eun RohDivision of Endocrinology and Metabolism, Department of Internal Medicine, Seoul National University Boramae Medical Center, Seoul National University College of Medicine, 20, Boramae-ro 5-gil, Dongjak-gu, Seoul, 07061, Republic of Korea. roheun@gmail.com.

Funding

Korea Health Industry Development Institute HI15C3153National Research Foundation of Korea RS-2024-00351464
6 · The paper itself

Abstract

The weight-adjusted waist index (WWI) is recognized as an indicator of age-related changes in body composition. This study aimed to investigate the impact of WWI on the development of sarcopenia in community-dwelling older adults. A total of 1,724 individuals aged 70-84 years without sarcopenia at baseline (defined by AWGS 2019 criteria) from the Korean Frailty and Aging Cohort Study were followed for two years. WWI was calculated as waist circumference (cm) divided by the square root of body weight (kg). Muscle mass was assessed using appendicular skeletal muscle mass adjusted for body mass index (ASM/BMI), and muscle strength was measured by handgrip strength (HGS). WWI was negatively associated with ASM/BMI (r = -0.354, P < 0.001) and HGS (r = -0.075, P = 0.002), as determined by Spearman partial correlation analysis adjusted for age and sex. During the two-year follow-up, 167 participants (9.7%) developed sarcopenia. Participants in the highest quartile of baseline WWI had a significantly higher risk of developing sarcopenia compared to those in the lowest quartile (OR 2.03, 95% CI [1.24, 3.32]), after adjusting for age, sex, current smoking, regular drinking, low physical activity, low income, hypertension, diabetes, dyslipidemia, and chronic kidney disease, HOMA-IR, hs-CRP, and 25(OH)-vitamin D. A higher baseline WWI was found to be an independent risk factor for the development of sarcopenia in older adults. WWI may serve as a simple and clinically useful tool for early identification of older adults at risk for sarcopenia.

Indexed as

SarcopeniaWaist CircumferenceAgedAged, 80 and overBody Mass IndexFemaleHand StrengthHumansIndependent LivingMaleProspective StudiesRepublic of KoreaRisk FactorsAged, epidemiologyMuscle strengthSarcopenia, skeletal muscleWeight adjusted waist index

Identifiers

PMID41639212
PMCPMC12923594

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.