Evidence map›Paper›PMID 41638650›Full record

ArticleEndocrine journal2026

Fibroblast growth factor 21-inducing rare sugars prevent diet-induced obesity in male BL/6 mice.

Oulan Ghnb Efendi, Sho Matsui, Daisuke Kohno, Satoshi Tsuzuki, Tadahiro Kitamura, Tsutomu Sasaki

Abstract read
In one paragraph

Article in Endocrine journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Oulan Ghnb EfendiLaboratory of Nutrition Chemistry, Division of Food Science and Biotechnology, Graduate School of Agriculture, Kyoto University, Kyoto 606-8502, Japan.
Sho MatsuiLaboratory of Nutrition Chemistry, Division of Food Science and Biotechnology, Graduate School of Agriculture, Kyoto University, Kyoto 606-8502, Japan.ORCID http://orcid.org/0000-0003-1256-1182
Daisuke KohnoLaboratory of Metabolic Signal, Institute for Molecular and Cellular Regulation, Gunma University, Gunma 371-8512, Japan.ORCID http://orcid.org/0009-0001-1073-2745
Satoshi TsuzukiLaboratory of Nutrition Chemistry, Division of Food Science and Biotechnology, Graduate School of Agriculture, Kyoto University, Kyoto 606-8502, Japan.ORCID http://orcid.org/0000-0003-4385-0075
Tadahiro KitamuraLaboratory of Metabolic Signal, Institute for Molecular and Cellular Regulation, Gunma University, Gunma 371-8512, Japan.ORCID http://orcid.org/0000-0001-8809-8740
Tsutomu SasakiLaboratory of Nutrition Chemistry, Division of Food Science and Biotechnology, Graduate School of Agriculture, Kyoto University, Kyoto 606-8502, Japan.ORCID http://orcid.org/0000-0001-8041-1915

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The consumption of a high-fat, high-sucrose diet (HFHSD) promotes obesity. Although dietary sugars are obesogenic, they activates a negative feedback mechanism between hepatic fibroblast growth factor 21 (FGF21) and oxytocin neurons in the paraventricular nucleus of the hypothalamus (PVH

Indexed as

Dietary SugarsFibroblast Growth FactorsFructoseHexosesObesitySorbitolAdiposityAnimalsDietary SucroseDiet, High-FatEnergy IntakeEnergy MetabolismGlucose IntoleranceInsulin ResistanceMaleMiceDietary SucroseDietary Sugarsfibroblast growth factor 21Fibroblast Growth FactorsFructoseHexosespsicoseSorbitolDiet-induced obesityFibroblast growth factor 21Obesity preventionRare sugar

Identifiers

PMID41638650
PMCPMC13271859

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.