Evidence map›Paper›PMID 41638604›Full record

ReviewAmerican journal of physiology. Lung cellular and molecular physiology2026

Platelet-mast cell dialogue in innate immune response and inflammation.

Saptarshi Roy, Pawan Sharma

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in American journal of physiology. Lung cellular and molecular physiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Saptarshi RoyDepartment of Pathology and Laboratory Medicine, Thoracic Medicine and Surgery, Center for Inflammation and Lung Research, Aging + Cardiovascular Discovery Center, Lewis Katz School of Medicine, Temple University, Philadelphia, Pennsylvania, United States.
Pawan SharmaDepartment of Pathology and Laboratory Medicine, Thoracic Medicine and Surgery, Center for Inflammation and Lung Research, Aging + Cardiovascular Discovery Center, Lewis Katz School of Medicine, Temple University, Philadelphia, Pennsylvania, United States.ORCID 0000-0002-2904-2306

Funding

E3 ubiquitin ligase RNF145 in airway smooth muscle functions and in asthmaR01HL161205 · NHLBI · THOMAS JEFFERSON UNIVERSITY · PI Pawan Sharma · 2022 to 2026
$2.4M
HHS | NIH | National Heart, Lung, and Blood Institute (NHLBI) HLRO1161205NHLBI NIH HHS R01 HL161205
6 · The paper itself

Abstract

Emerging evidence identifies platelets as active participants in inflammation beyond their traditional hemostatic function. Mast cells, tissue-resident granulocytes, are key players in innate immunity. Recent studies reveal dynamic bidirectional interaction between these two cell types. An IL33-driven feed-forward circuit has been described, in which mast cell-derived leukotriene C

Indexed as

Blood PlateletsCell CommunicationImmunity, InnateInflammationMast CellsAnimalsHumansSignal Transductionairwayimmune responseinflammationmast cellsplatelets

Identifiers

PMID41638604
PMCPMC12951121

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.