ArticleForensic science, medicine, and pathology2026
Forensic identification of Agkistrodon halys bite by the combination of ELISA and immunohistochemistry: a case report and literature review.
Article in Forensic science, medicine, and pathology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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1 citing paper in PubMed.
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8 authors.
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Abstract
Snakebites constitute a significant global public health concern. Based on various toxic components and action mechanisms, snake venoms are typically classified into hemotoxic, neurotoxic, and histotoxic types. The pathological changes caused by different toxicities vary, which is often one of the key points in the forensic identification of snake bites. However, relying solely on this aspect often has certain limitations in the identification of snake bite cases, with poor qualitative and quantitative results. This article presents a case of identifying death caused by an Agkistrodon halys bite through the combined application of ELISA and immunohistochemistry (IHC) methods. The concentration of snake venom in the subcutaneous tissue at the fang marks was precisely measured at 6.58 ng/mL. In addition, we summarized the forensic characteristics of such snake venom poisoning by a retrospective analysis of the literature, aiming to provide reference for the forensic identification.
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