Evidence map›Paper›PMID 41636746›Full record

ArticleLab on a chip2026

Nanofluidic-based electrochemical pump for remotely controlled, on-demand drug delivery.

Marco M Paci, Nicola Di Trani, Paolo Bolla, Fabiana Del Bono, Takuma Yoshikawa, Isaac Tichy, Patrick S Stayton, Alessandro Grattoni

Abstract read
In one paragraph

Article in Lab on a chip, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Marco M PaciDepartment of Nanomedicine, Houston Methodist Research Institute, Houston, TX 77030, USA. agrattoni@houstonmethodist.org.
Nicola Di TraniDepartment of Nanomedicine, Houston Methodist Research Institute, Houston, TX 77030, USA. agrattoni@houstonmethodist.org.ORCID 0000-0002-4780-7915
Paolo BollaDepartment of Nanomedicine, Houston Methodist Research Institute, Houston, TX 77030, USA. agrattoni@houstonmethodist.org.
Fabiana Del BonoDepartment of Nanomedicine, Houston Methodist Research Institute, Houston, TX 77030, USA. agrattoni@houstonmethodist.org.ORCID 0000-0001-6194-031X
Takuma YoshikawaDepartment of Bioengineering, University of Washington, Seattle, WA 98195, USA.
Isaac TichyDepartment of Nanomedicine, Houston Methodist Research Institute, Houston, TX 77030, USA. agrattoni@houstonmethodist.org.
Patrick S StaytonDepartment of Bioengineering, University of Washington, Seattle, WA 98195, USA.ORCID 0000-0001-6939-6371
Alessandro GrattoniDepartment of Nanomedicine, Houston Methodist Research Institute, Houston, TX 77030, USA. agrattoni@houstonmethodist.org.ORCID 0000-0001-7888-422X

Funding

A nanofluidic platform for tunable drug deliveryR01GM127558 · NIGMS · METHODIST HOSPITAL RESEARCH INSTITUTE · PI GRATTONI, ALESSANDRO, LIU, XUEWU · 2018 to 2021
$1.6M
Gates Foundation INV-027674NIGMS NIH HHS R01 GM127558
6 · The paper itself

Abstract

Implantable drug delivery systems offer the promise of on-demand, tunable release profiles tailored to individual therapeutic needs. Here, we present a nanofluidic membrane-based electrochemical delivery system that leverages controlled

Indexed as

Drug Delivery SystemsElectrochemical TechniquesLab-On-A-Chip DevicesMicrofluidic Analytical TechniquesNanotechnologyDrug LiberationEquipment Design

Identifiers

PMID41636746
PMCPMC12871488

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.