ArticleJournal of managed care & specialty pharmacy2026
Socioeconomic, demographic, and medication class determinants of medication adherence: A retrospective cohort study.
Article in Journal of managed care & specialty pharmacy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundMedication adherence varies across socioeconomic and demographic groups. Prior work has examined these relationships in selected populations and with zip code-level socioeconomic measures, but less is known about adherence patterns across all medications when using more granular community measures and location proxies.
objectiveTo quantify associations between socioeconomic, demographic, and medication class factors and outpatient medication adherence.
methodsWe conducted a retrospective cohort study of 1,252,986 outpatient medication orders for 189,832 adults placed at a large health system in the Mountain West (University of Utah Health) from January 1, 2022, to January 1, 2024. Pharmacy, electronic health record, and Surescripts data were used. Medication adherence (proportion of days covered) was modeled with multivariate β regression with covariates including insurance, race, sex, marital and employment status, medication class, and Social Vulnerability Index socioeconomic quartile.
resultsMedicaid (adjusted odds ratio [aOR] = 0.87,
conclusionsSeveral individual-level factors had strong associations with adherence. Community-level socioeconomic vulnerability had a modest association.
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