Evidence map›Paper›PMID 41636342›Full record

SynthesisActa dermato-venereologica2026

Effects of Psychological Interventions on Itch, Scratching, and Excoriations: A Systematic Review and Meta-analysis.

Christina Schut, Johanna Munz, Frederic Maas Genannt Bermpohl, Antoinette I M Van Laarhoven, Jennifer Schmidt, Andrea W M Evers, Jörg Kupfer

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in Acta dermato-venereologica, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Christina SchutJustus-Liebig-University Giessen, Department of Medicine, Institute of Medical Psychology, Germany; University of Applied Sciences for Public Management and Security, Faculty of Police, Wiesbaden, Germany. Christina.Schut@psycho.med.uni-giessen.de.ORCID 0000-0001-5366-6285
Johanna MunzJustus-Liebig-University Giessen, Department of Medicine, Institute of Medical Psychology, Germany.ORCID 0009-0003-9892-4366
Frederic Maas Genannt BermpohlUniversity of Wuppertal, Department of Clinical Psychology and Psychotherapy, School of Human and Social Sciences, Germany.ORCID 0000-0002-2370-4946
Antoinette I M Van LaarhovenLeiden University, Health, Medical and Neuropsychology Unit, Faculty of Social and Behavioural Sciences, The Netherlands.ORCID 0000-0001-6932-9283
Jennifer SchmidtFH Muenster University of Applied Sciences, Muenster Department of Health, Germany.
Andrea W M EversLeiden University, Health, Medical and Neuropsychology Unit, Faculty of Social and Behavioural Sciences, The Netherlands.ORCID 0000-0002-0090-5091
Jörg KupferJustus-Liebig-University Giessen, Department of Medicine, Institute of Medical Psychology, Germany.ORCID 0000-0002-9905-8485

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Psychological interventions reduce itch in patients with skin diseases. However, previous systematic reviews and meta-analyses did not include patients with non-skin-related chronic itch and did not consider excoriations as outcome. This study therefore summarized randomized controlled trials investigating effects of psychological interventions on itch, scratching, and excoriations in patients with chronic itch due to all causes. A systematic literature search was conducted. A random effects model was used to aggregate between-group effect sizes. It was found that 17 of the 20 trials included patients with atopic dermatitis. Small to large post-treatment and follow-up effects were observed on self-rated itch intensity (post-treatment: k = 12, g = -0.37 [-0.60; -0.15]; follow-up: k = 6; g = -0.59 [-0.97; -0.21]), externally rated excoriations (post-treatment: k = 6, g = -0.29 [-0.49; -0.09]; follow-up: k = 6; g = -0.34 [-0.53; -0.15]), and self-rated scratching intensity (post-treatment: k = 2, g = -0.99 [-1.35; -0.63]; follow-up: k = 2; g = -0.85 [-1.22; -0.48]). Small post-treatment effects were observed on self-rated itch frequency (k = 3, g = -0.22 [-0.40; -0.04]). Thus, psychological interventions show promise in reducing not only itch and scratching, but also excoriations, with effects lasting up to 1 year.

Indexed as

Excoriation DisorderPruritusPsychosocial InterventionChronic DiseaseDermatitis, AtopicFemaleHumansMaleRandomized Controlled Trials as TopicTreatment Outcome

Identifiers

PMID41636342
PMCPMC12882111

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.