Evidence map›Paper›PMID 41636305›Full record

ArticleInternational journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics2026

Hysterectomy for placenta accreta spectrum disorder: Impact of institutional surgical volume on patient outcomes.

Lacey C Brennan, Olga Bougie, Jonas Shellenberger, Jessica Pudwell, John Kingdom, Peter S Thiel, Lisa Allen, Sebastian R Hobson, Maria P Velez, Ally Murji

Abstract read
In one paragraph

Article in International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Lacey C BrennanDepartment of Obstetrics and Gynecology, Peter Lougheed Center, Calgary, Alberta, Canada.ORCID https://orcid.org/0000-0001-9859-2654
Olga BougieDepartment of Obstetrics and Gynecology, Mount Sinai Hospital, Toronto, Ontario, Canada.
Jonas ShellenbergerInstitute of Clinical Evaluative Sciences (ICES), Kingston, Ontario, Canada.
Jessica PudwellDepartment of Obstetrics and Gynecology, Queen's University, Kingston Health Sciences Center, Kingston General Hospital, Kingston, Ontario, Canada.
John KingdomDepartment of Obstetrics and Gynecology, Mount Sinai Hospital, Toronto, Ontario, Canada.
Peter S ThielDepartment of Obstetrics and Gynecology, Royal University Hospital, University of Saskatchewan, Saskatoon, Saskatchewan, Canada.
Lisa AllenDepartment of Obstetrics and Gynecology, Mount Sinai Hospital, Toronto, Ontario, Canada.
Sebastian R HobsonDepartment of Obstetrics and Gynecology, Mount Sinai Hospital, Toronto, Ontario, Canada.
Maria P VelezInstitute of Clinical Evaluative Sciences (ICES), Kingston, Ontario, Canada.
Ally MurjiDepartment of Obstetrics and Gynecology, University of Toronto, Toronto, Ontario, Canada.

Funding

Joseph M. West Family Memorial FundMount Sinai Hospital, Department of Obstetrics and Gynecology
6 · The paper itself

Abstract

objectiveTo evaluate trends in hysterectomy case volume for placenta accreta spectrum (PAS) disorder over time and compare maternal outcomes between high- and low-volume centers. Specifically, we examined whether surgical volume influences severe maternal morbidity (SMM) and other key perioperative outcomes.

methodsWe conducted a population-based retrospective cohort study of patients aged 18-50 years who underwent hysterectomy for PAS in Ontario, Canada, from January 1, 2003, to January 1, 2022. Cases were identified using provincial administrative health databases. High-volume centers were defined as institutions performing ≥9 PAS hysterectomies annually, based on probability modeling and receiver operating characteristic analysis. The primary outcome was a validated composite measure of SMM, including massive transfusion, intensive care unit (ICU) admission, surgical complications, readmission, and length of hospital stay.

resultsAmong 778 patients, 151 were treated at high-volume centers. These patients experienced significantly lower rates of SMM compared to those treated at low-volume centers (45.0% vs. 71.7%; adjusted relative risk [aRR] 0.59, 95% confidence interval [CI]: 0.49-0.72). Risks of massive transfusion (aRR 0.57, 95% CI: 0.47-0.70) and ICU admission (aRR 0.30, 95% CI: 0.15-0.58) were also markedly reduced. Length of hospital stay was shorter at high-volume centers (1.88 vs. 3.90 days; P < 0.0001). Each additional PAS hysterectomy performed in the prior year at a given institution was associated with a 3% reduction in SMM risk (aRR 0.97, 95% CI: 0.96-0.98).

conclusionHigh-volume centers demonstrate significantly better maternal outcomes for PAS hysterectomy. These findings support centralizing PAS care to improve patient safety and surgical outcomes.

Indexed as

Hospitals, High-VolumeHospitals, Low-VolumeHysterectomyPlacenta AccretaAdolescentAdultBlood TransfusionFemaleHumansIntensive Care UnitsLength of StayMiddle AgedOntarioPostoperative ComplicationsPregnancyRetrospective Studieshysterectomyinvasive placentationmaternal morbidityplacenta accreta spectrumsurgical volume

Identifiers

PMID41636305
PMCPMC13278653

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.