Article in European journal of immunology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what money
Authors and funding
10 authors.
Diana TintorDivision of Immunology and University Children's Hospital Research Center, University Children's Hospital Zurich, Zurich, Switzerland.ORCID 0009-0001-7292-8284
Samantha MilanesiDivision of Immunology and University Children's Hospital Research Center, University Children's Hospital Zurich, Zurich, Switzerland.
Tommaso MarchettiDivision of Immunology and University Children's Hospital Research Center, University Children's Hospital Zurich, Zurich, Switzerland.
Tiziana LorenziniDivision of Immunology and University Children's Hospital Research Center, University Children's Hospital Zurich, Zurich, Switzerland.
Severin WalserDivision of Immunology and University Children's Hospital Research Center, University Children's Hospital Zurich, Zurich, Switzerland.ORCID 0009-0005-3165-1441
Junyi ChenDivision of Immunology and University Children's Hospital Research Center, University Children's Hospital Zurich, Zurich, Switzerland.
Julius KöppenDivision of Immunology and University Children's Hospital Research Center, University Children's Hospital Zurich, Zurich, Switzerland.
Achim WeberDepartment of Pathology and Molecular Pathology, University Hospital Zurich and University of Zurich, Zurich, Switzerland.
Ola SabetDivision of Immunology and University Children's Hospital Research Center, University Children's Hospital Zurich, Zurich, Switzerland.
Jana Pachlopnik SchmidDivision of Immunology and University Children's Hospital Research Center, University Children's Hospital Zurich, Zurich, Switzerland.ORCID 0000-0002-6653-9047
Funding
CYTIMM-Z Clinical Research Priority ProgramITINERARE University Research Priority ProgramSwiss National Science Foundation 320030_205097Wolfermann-Nägeli-Stiftung 2024/29
6 · The paper itself
Abstract
Hemophagocytic lymphohistiocytosis (HLH) is a severe inflammatory syndrome characterized by persistent activation of lymphocytes and macrophages. Recently, deleterious autosomal recessive mutations in ZNFX1 were reported to predispose pediatric patients to HLH-like disease upon viral trigger. The objective of this study was to assess the suitability of Znfx1-mutant (Znfx1
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.
A Novel Murine Model of Hemophagocytic Lymphohistiocytosis-Like Inflammation in ZNFX1 Deficiency. · full record | OpenQuestion