Evidence map›Paper›PMID 41635787›Full record

ArticleFrontiers in veterinary science2025

Potentiated zinc and monovalent copper oxide as dietary supplements for weanling piglets: effects on systemic and mucosal immunity, gut permeability, and fecal microbiota composition.

Luca Marchetti, Raffaella Rebucci, Paola Cremonesi, Filippo Biscarini, Bianca Castiglioni, Davide Lanzoni, Alessandra Monteiro, Yron Joseph Yabut Manaig, Valentino Bontempo

Abstract read
In one paragraph

Article in Frontiers in veterinary science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Luca MarchettiDepartment of Veterinary Medicine and Animal Sciences (DIVAS), University of Milan, Lodi, Italy.
Raffaella RebucciDepartment of Veterinary Medicine and Animal Sciences (DIVAS), University of Milan, Lodi, Italy.
Paola CremonesiNational Research Council, Institute of Agricultural Biology and Biotechnology (IBBA-CNR), Lodi, Italy.
Filippo BiscariniNational Research Council, Institute of Agricultural Biology and Biotechnology (IBBA-CNR), Lodi, Italy.
Bianca CastiglioniNational Research Council, Institute of Agricultural Biology and Biotechnology (IBBA-CNR), Lodi, Italy.
Davide LanzoniDepartment of Veterinary Medicine and Animal Sciences (DIVAS), University of Milan, Lodi, Italy.
Alessandra MonteiroAnimine, Annecy, France.
Yron Joseph Yabut ManaigAnimine, Annecy, France.
Valentino BontempoDepartment of Veterinary Medicine and Animal Sciences (DIVAS), University of Milan, Lodi, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study examines the potential of modulating gut health parameters in piglets by varying zinc/copper ratios administered through specialty oxide sources. A total of 84 piglets were selected after weaning and divided into four experimental treatment groups; the trial lasted 28 days. During the initial phase (1-14 d), the positive control (PC) received 2500 ppm of zinc, provided as conventional zinc oxide. In parallel, three additional treatment groups were formed, in which copper (Cu) and zinc (Zn) were supplemented using potentiated zinc oxide (Pot-ZnO) and monovalent copper oxide (Cu

Indexed as

animal healthgut healthgut microbiomeimmune responseintestinal barriernutritiontrace elementsweaning

Identifiers

PMID41635787
PMCPMC12862941

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.