Evidence map›Paper›PMID 41635724›Full record

ArticlePlastic and reconstructive surgery. Global open2026

The Role and Efficacy of NovoSorb Biodegradable Temporizing Matrix in Complex Reconstructive Wounds: A Systematic Review.

Omar H Shadid, Siuyan Pang, Basheer N Arnaout, Aleha Pillay, Beryl Tan, Cheng H Lo

Abstract read
In one paragraph

Article in Plastic and reconstructive surgery. Global open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Omar H ShadidFrom the Plastics and Reconstructive Surgery Department, The Royal Melbourne Hospital, Parkville, Victoria, Australia.
Siuyan PangFrom the Plastics and Reconstructive Surgery Department, The Royal Melbourne Hospital, Parkville, Victoria, Australia.
Basheer N ArnaoutFaculty of Medicine, Dentistry and Health Sciences, The University of Melbourne, Parkville, Victoria, Australia.
Aleha PillayFaculty of Medicine and Health, The University of Sydney, Camperdown, New South Wales, Australia.
Beryl TanPlastics and Reconstructive Surgery Department, Western Health, St Albans, Victoria, Australia.
Cheng H LoFaculty of Medicine, Dentistry and Health Sciences, The University of Melbourne, Parkville, Victoria, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Managing complex wounds with exposed bone, tendons, metalware, or irradiated tissue is challenging. NovoSorb Biodegradable Temporizing Matrix (BTM) offers an alternative by promoting vascularization and neodermis formation. This review assessed the effectiveness of BTM in managing complex wounds, including those with vascular compromise (eg, periosteal stripping or denuded paratenon) or exposure to radiotherapy. Methods: A systematic search of Embase, Ovid, Scopus, and PubMed was conducted. Inclusion criteria included wounds involving exposed bone, tendons, or radiotherapy exposure. Data were analyzed for clinical outcomes, demographic variables, and complications. Results: A total of 208 patients across 34 studies were analyzed. The overall complication rate was 27.9%. Wounds with combined bone and tendon exposure and periosteal stripping or denuded paratenon had significantly higher complication rates than those with only exposed bone and tendon (57.1% versus 35.3%, Conclusions: BTM is a valuable addition to the reconstructive armamentarium. However, complication rates in complex wounds are high, so careful clinical judgment is essential for their implementation.

Identifiers

PMID41635724
PMCPMC12863789

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.