Evidence map›Paper›PMID 41635655›Full record

ArticleActa clinica Croatica2025

EFFECT OF PLATELET RICH FIBRIN ON WOUND HEALING TIME AFTER REVASCULARIZATION.

Mijo Mravičić, Ana Adžić-Kapitanović, Andrej Razumić, Marta Bakšić, Vedran Pažur, Tena Magovac, Marko Granić

Abstract read
In one paragraph

Article in Acta clinica Croatica, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Mijo MravičićDepartment of Vascular Surgery, Merkur University Hospital, Zagreb, Croatia.
Ana Adžić-KapitanovićDepartment of Surgery, Merkur University Hospital, Zagreb, Croatia.
Andrej RazumićDepartment of Quality, Faculty of Mechanical Engineering and Naval Architecture, University of Zagreb, Zagreb, Croatia.
Marta BakšićDepartment of Vascular Surgery, Merkur University Hospital, Zagreb, Croatia.
Vedran PažurDepartment of Vascular Surgery, Merkur University Hospital, Zagreb, Croatia.
Tena MagovacDepartment of Vascular Surgery, Merkur University Hospital, Zagreb, Croatia.
Marko GranićDepartment of Oral Surgery, School of Dental Medicine, University of Zagreb, Zagreb University Hospital Center, Zagreb, Croatia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

One of the most common diseases in vascular surgery is peripheral arterial disease, the last stage of which is critical limb ischemia. It is characterized by rest pain or tissue loss. In most cases, after revascularization, and due to gangrenous changes, it is necessary to perform amputation of a part of the lower limb. After amputation, the wound is bandaged with dressings. In conducting this pilot study, some patients were bandaged with platelet rich fibrin (PRF) in combination with dressings, while the others were treated only with dressings. PRF is a biologic material that is received from blood of the patient. All patients included in the trial had at least 2 out of 3 traversable blood vessels in the lower leg before treatment and underwent femoropopliteal bridging with prosthesis. Patients treated with PRF after revascularization had an average of 5 weeks of wound healing, in contrast to patients treated only with dressings, whose mean wound healing was 8.5 weeks and a proportion of these patients ended up with an extended amputation level. After the study, it is concluded that this type of treatment can be safely used in the treatment of vascular pathology.

Indexed as

AmputationCritical limb ischemiaPeripheral arterial diseasePlatelet rich fibrin

Identifiers

PMID41635655
PMCPMC12863282

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.