SynthesisFrontiers in neurology2025
Efficacy of oblique pulling manipulation combined with adjunct therapies (massage/acupuncture/herbal medicine/injection) for lumbar disc herniation: a systematic review and meta-analysis of pain and functional outcome.
Synthesis in Frontiers in neurology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Trial
- Optimizing lumbar therapy: a biomechanical study of oblique pulling manipulation under different postures.BMC complementary medicine and therapies · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: This study aimed to systematically evaluate the clinical efficacy of oblique pulling manipulation and its combination with massage, acupuncture, Chinese herbal medicine, and injection therapy in lumbar disc herniation (LDH). Methods: The meta-analysis followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines and was registered with PROSPERO (CRD420251107984). A comprehensive search was conducted in databases including China National Knowledge Infrastructure (CNKI), Wanfang Database, Chinese Scientific Journals Database (VIP), Chinese Biomedical Literature Database (CBM), PubMed, EMBASE, Web of Science, and the Cochrane Library until June 2025. All statistical analyses were conducted using Review Manager 5.4.1. Dichotomous outcomes were summarized as odds ratios (ORs) with 95% confidence intervals (CIs), and continuous outcomes were summarized as standardized mean differences (SMDs) with 95% CIs. Results: A total of 26 studies comprising 2,766 patients with lumbar disc herniation were included. The results of the meta-analysis revealed that oblique pulling manipulation and its combination with massage, acupuncture, Chinese herbal medicine, and injection therapy in LDH significantly improved the effective rate and cure rate in patients with LDH. In addition, oblique pulling manipulation significantly improved the Japanese Orthopedic Association (JOA) score, and oblique pulling manipulation combined with massage or acupuncture decreased the Oswestry Disability Index (ODI). Discussion: Oblique pulling manipulation and its combination with massage, acupuncture, Chinese herbal medicine, and injection therapy improved efficacy and cure rates in patients with lumbar disc herniation. Future research should focus on standardizing treatment protocols and extending follow-up periods to confirm long-term safety and effectiveness, thereby ensuring broader applicability and better patient outcomes. Systematic review registration: https://www.crd.york.ac.uk/prospero/CRD420251107984, identifier: CRD420251107984.
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Registered trials
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