ArticleCureus2026
Labial Angioedema and Bacterial and Viral Infection Following Hyaluronic Acid Injection.
Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Hyaluronic acid (HA) currently maintains a favorable safety profile in the field of aesthetic medicine. However, severe acute hypersensitivity reactions may occur, clinically defined as angioedema. This condition typically presents immediately after HA injection, with marked swelling, pain, and evident tissue distress secondary to edema and local vascular physiological alterations. These events are more frequently observed in the lips, and although reported cases are scarce, most involve this anatomical location. The etiology of this uncommon complication is not fully understood. Proposed mechanisms include trace protein impurities within HA preparations, as well as the role of CD44-expressing mast cells, which exhibit strong adherence to tissue-bound HA. We present a case report of a patient who developed labial angioedema following HA injection, clinically associated with both viral and bacterial infection. The clinical presentation, diagnostic workup, therapeutic approach, and clinical outcome are described.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.