Evidence map›Paper›PMID 41635567›Full record

ArticleCureus2026

Concurrent Presentation of Idiopathic Intracranial Hypertension and Bilateral Optic Perineuritis in a Young Boy: A Rare Clinical Entity.

Olga Vampertzi, Eleni Vouxinou, Asimina Mataftsi, Fotini Goutsaridou, Maria Fotoulaki, Dimitrios Zafeiriou

Abstract readCase Reports
In one paragraph

Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Olga Vampertzi4th Department of Pediatrics, School of Medicine, Faculty of Health Sciences, Papageorgiou General Hospital, Aristotle University of Thessaloniki, Thessaloniki, GRC.
Eleni Vouxinou4th Department of Pediatrics, School of Medicine, Faculty of Health Sciences, Papageorgiou General Hospital, Aristotle University of Thessaloniki, Thessaloniki, GRC.
Asimina Mataftsi2nd Department of Ophthalmology, School of Medicine, Faculty of Health Sciences, Papageorgiou General Hospital, Aristotle University of Thessaloniki, Thessaloniki, GRC.
Fotini GoutsaridouDepartment of Radiology, School of Medicine, Faculty of Health Sciences, Papageorgiou General Hospital, Aristotle University of Thessaloniki, Thessaloniki, GRC.
Maria Fotoulaki4th Department of Pediatrics, School of Medicine, Faculty of Health Sciences, Papageorgiou General Hospital, Aristotle University of Thessaloniki, Thessaloniki, GRC.
Dimitrios Zafeiriou1st Department of Pediatrics, School of Medicine, Faculty of Health Sciences, Hippokratio General Hospital, Aristotle University of Thessaloniki, Thessaloniki, GRC.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Idiopathic intracranial hypertension (IIH) is a rare neurological syndrome characterized by increased intracranial pressure (>28 cm H₂O in children), in the absence of intracranial space-occupying lesions, and with normal cerebrospinal fluid (CSF) composition. Optic perineuritis (OPN) is an orbital inflammatory disease confined to the optic nerve sheath. We report a case of concurrent IIH and bilateral OPN in a previously healthy child. A 13-year-old male, with normal body mass index, presented with diplopia, visual blurriness without ocular pain, and occipital headache. Neurological examination was notable only for right sixth nerve palsy. Ophthalmological assessment revealed bilateral papilledema. Brain and spinal cord magnetic resonance imaging (MRI) and computed tomography (CT) scans demonstrated bilateral optic nerve perineuritis. Lumbar puncture showed an opening pressure of 98 cm H₂O, with normal CSF composition. The patient was treated with acetazolamide and corticosteroids, resulting in marked clinical improvement and complete restoration of vision at two-month follow-up. The concurrent occurrence of IIH and bilateral OPN is extremely rare, particularly in pediatric patients. To our knowledge, this is the first reported case in a child. Recognition of this dual pathology is essential for timely diagnosis and effective treatment.

Indexed as

childhooddiplopiaoptic perineuritispapilledemapseudotumor cerebri

Identifiers

PMID41635567
PMCPMC12863709

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.