Evidence map›Paper›PMID 41635519›Full record

ArticleFrontiers in psychiatry2025

Differences in height, weight, and BMI in patients with mood disorders, schizophrenia, and other mental disorders vs. normal controls.

Konstantinos N Fountoulakis, Nikoleta Petalidou, Nikolaos K Fountoulakis, Ioannis Nimatoudis, Pavlos N Theodorakis

Abstract read
In one paragraph

Article in Frontiers in psychiatry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Konstantinos N Fountoulakis3Department of Psychiatry, School of Medicine, Faculty of Health Sciences, Aristotle University, Thessaloniki, Greece.
Nikoleta Petalidou3Department of Psychiatry, School of Medicine, Faculty of Health Sciences, Aristotle University, Thessaloniki, Greece.
Nikolaos K Fountoulakis3Department of Psychiatry, School of Medicine, Faculty of Health Sciences, Aristotle University, Thessaloniki, Greece.
Ioannis Nimatoudis3Department of Psychiatry, School of Medicine, Faculty of Health Sciences, Aristotle University, Thessaloniki, Greece.
Pavlos N TheodorakisSenior Advisor, Health Policy, WHO Country Office Hungary, Regional Office for Europe, Budapest, Hungary.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: The literature suggests differences in the body between the general population and patients with mental disorders. The current study aimed to search for differences between healthy controls and patients with mental disorders in terms of body height, weight, BMI, and Body surface area (BSA). Material and methods: The study sample included 788 healthy control subjects, 76 patients with unipolar depression, 36 with Bipolar disorder, 16 patients with schizoaffective disorder, 122 patients with schizophrenia, and 78 patients with other mental disorders (a mixture of severe forms of OCD, psychotic and mood disorders other than the aforementioned, as well as severe personality disorders). The diagnosis was made according to DSM-IV-TR criteria, based on a semi-structured interview using the Schedules for Clinical Assessment in Neuropsychiatry version 2.0 (SCAN v 2.0). The height and weight of all subjects were measured. The Body mass index (BMI) and the Body surface area (BSA-D according to the Dubois method) were calculated. All variables were normalized using the rank and percentile method based on the percentiles obtained from the healthy control group. The statistical analysis included a MANCOVA with the Scheffé Results: The results suggested that depressed patients are shorter than expected, while higher BMI was observed in depressed females only. No other differences among groups were identified. Discussion: The current study implies the presence of a developmental component in unipolar depression since this mental disorder is associated with a body measure (height) whose development is completed by late adolescence. An explanation could involve the presence of a biased negativistic assessment of the environment, which affects the functioning of the central melanocortin system, which controls appetite, food intake, and energy expenditure, and it is directly related to body development.

Indexed as

BMIbody surface areabody surface areaheightmental disordersweight

Identifiers

PMID41635519
PMCPMC12862057

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.