Evidence map›Paper›PMID 41635470›Full record

Trial reportFrontiers in medicine2026

Tuina therapy plus resistance exercise vs. Tuina alone for mechanical neck pain: a randomized controlled trial.

San Zheng, Zhiwei Wu, Yaping Chang, Hua Xing, Yiming Shan, Yangyang Fu, Yazhou Li, Zhiran Kang, Jintian Chen, Jiangshan Li and 4 more

Abstract readClinical Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Frontiers in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

San ZhengDepartment of Tuina, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Zhiwei WuDepartment of Tuina, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Yaping ChangDepartment of Health Research Methods, Evidence & Impact (HEI), Faculty of Health Sciences, McMaster University, Hamilton, ON, Canada.
Hua XingDepartment of Tuina, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Yiming ShanDepartment of Tuina, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Yangyang FuDepartment of Tuina, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Yazhou LiDepartment of Tuina, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Zhiran KangDepartment of Tuina, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Jintian ChenDepartment of Tuina, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Jiangshan LiDepartment of Tuina, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Jie LiDepartment of Tuina, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Junliang WangDepartment of Tuina, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Min FangDepartment of Tuina, Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Wuquan SunDepartment of Tuina, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Tuina and exercise therapy are widely used to treat mechanical neck pain (MNP), but evidence on their combined efficacy remains limited. This study evaluated the effectiveness of Tuina combined with resistance exercise (RE) versus Tuina alone in managing MNP. Methods: We conducted a 4-week, analyst-blinded, randomized controlled trial with 90 participants with MNP. Participants were randomly assigned to receive either Tuina Therapy plus RE (TTRE, Results: The mean age of the 90 enrolled patients was 26.4 years [standard deviation (SD), 3.1 and 49 (54.4%) were female]. The mean difference in VAS scores from baseline at week 4 for TTRE group was -4.2 (95% CI, -4.4 to -4.0). At week 4, the difference in VAS score was 0.5(95% CI, 0.30 to 0.77; Conclusion: In this study, participants with MNP in the TTRE group showed statistically greater improvements than those in the Tuina group in pain reduction, functional recovery, extension PSCM, and flexion CROM at week 4. TTRE may be considered a valuable option in the management of MNP. Clinical trial registration: We registered the trial with the Chinese Clinical Trial Registry (ChiCTR2300068344; Registration Date: February 15, 2023) at http://www.chictr.org.cn.

Indexed as

complementary and alternative medicineisometric contraction trainingmechanical neck painresistance exerciseTuina therapy

Identifiers

PMID41635470
PMCPMC12862936

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.