Evidence map›Paper›PMID 41635453›Full record

Trial reportJournal of medicine and life2025

Efficacy and safety of Ashwagandha (

Ketan Pakhale, Rajshree Pakhale, Mayakalyani Srivathsan, Jayshree Langade, Deepak Langade

Abstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Journal of medicine and life, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Safety and tolerability of Ashwagandha (Frontiers in nutrition · 2026
    Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ketan PakhaleMetabolic Syndrome, Metabol-Lifestyle Clinic for Metabolic Syndrome, Mumbai, Maharashtra, India.
Rajshree PakhaleClinical Research, Clinsearch Healthcare Solutions, Thane, Maharashtra, India.
Mayakalyani SrivathsanPharmacology, D Y Patil University School of Medicine, Nerul, Navi Mumbai, Maharashtra, India.
Jayshree LangadeClinical Research, Clinsearch Healthcare Solutions, Thane, Maharashtra, India.
Deepak LangadePharmacology, D Y Patil University School of Medicine, Nerul, Navi Mumbai, Maharashtra, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The relationship between excess body weight and stress significantly impacts overall health. The current study evaluated the efficacy and safety of Ashwagandha (

Indexed as

Body WeightPlant ExtractsPlant RootsStress, PsychologicalWithaniaAdultAgedBody Mass IndexDouble-Blind MethodFemaleHumansMaleMiddle AgedProspective StudiesQuality of LifeYoung AdultAshwagandhaPlant ExtractsAEs, adverse eventsANOVA, analysis of varianceARE, Ashwagandha root extractBMI, body mass indexCA2, carbonic anhydrase IICA3, carbonic anhydrase IIICBC, complete blood countCLIA, chemiluminescent immunoassayCONSORT, Consolidated Standards of Reporting TrialsCTRI, Clinical Trials Registry of IndiaFCQ-T, Food Cravings Questionnaire-TraitGLM, General Linear ModelHPA, hypothalamic-pituitary-adrenal axisICH-GCP, International Council for Harmonisation Good Clinical PracticeIEC, Institutional Ethics CommitteeLFT, liver function testsMCS, Mental Component SummaryoverweightPCS, Physical Component SummaryPL, placeboPSS, Perceived Stress ScalepsychologicalRCT, randomized controlled trialsafetySD, standard deviationSSS, Subjective Satisfaction ScalestressT3, triiodothyronineT4, thyroxineTEAEs, treatment-emergent adverse eventsWithania somnifera

Identifiers

PMID41635453
PMCPMC12863098

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.