Evidence map›Paper›PMID 41635381›Full record

ArticleCureus2026

Long-Term Nonprogressive Interstitial Lung Disease in Anti-PL-12- and Anti-Ro52-Positive Antisynthetase Syndrome Without Immunosuppressive Therapy.

Bsher Almaalouli, Harini Reddy Choula, Miguel Rodriguez

Abstract readCase Reports
In one paragraph

Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Bsher AlmaalouliInternal Medicine, University of Central Florida College of Medicine, Orlando, USA.
Harini Reddy ChoulaInternal Medicine, University of Central Florida College of Medicine, Orlando, USA.
Miguel RodriguezRheumatology, SIMEDHealth, Gainesville, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Antisynthetase syndrome (ASS) is an autoimmune condition associated with aminoacyl-tRNA synthetases (ARS) antibodies and often presents with interstitial lung disease (ILD). We describe a patient with ILD and positive anti-PL-12 and anti-Ro52 antibodies. Although these antibodies are generally linked with more active or progressive lung disease, this patient remained clinically stable for several years without immunosuppressive therapy. This case illustrates the broad variability in the clinical expression and course of anti-PL-12-associated disease and shows that some individuals may experience long periods of remission despite serologic profiles often considered high-risk.

Indexed as

anti-ro52 antibodyantisynthetase syndromeinterstitial lung disease and anti-pl-12 antibodymechanic’s handstreatment-free remission

Identifiers

PMID41635381
PMCPMC12862984

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.