Evidence map›Paper›PMID 41635379›Full record

ArticleCureus2026

Cutaneous Eruptions as a Consequence of Myeloid Leukemic Infiltration: Differential Diagnosis With a Benign Dermatosis.

Tiago S Duarte, Cristiana L Matos, Ricardo C Martins

Abstract readCase Reports
In one paragraph

Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Tiago S DuarteFamily Medicine, Unidade Local de Saúde de Entre Douro e Vouga (ULSEDV) - Unidade de Saúde Familiar (USF) Alpha, Ovar, PRT.
Cristiana L MatosFamily Medicine, Unidade Local de Saúde de Entre Douro e Vouga (ULSEDV) - Unidade de Saúde Familiar (USF) Alpha, Ovar, PRT.
Ricardo C MartinsFamily Medicine, Unidade Local de Saúde de Entre Douro e Vouga (ULSEDV) - Unidade de Saúde Familiar (USF) Alpha, Ovar, PRT.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Leukemia cutis is an uncommon but clinically significant manifestation of hematologic malignancies caused by infiltration of the skin by malignant leukocytes. Its presentation is highly variable and may closely resemble benign inflammatory dermatoses, frequently leading to diagnostic delay. We report the case of a 76-year-old man with JAK2-positive essential thrombocythemia (ET) who developed persistent, intensely pruritic maculopapular skin lesions initially diagnosed as dermatitis. Despite symptomatic treatment, the lesions progressed and were followed by systemic symptoms. Further investigation revealed acute myeloid leukemia (AML) arising from blastic transformation of ET, with probable cutaneous involvement consistent with leukemia cutis. This case highlights the importance of maintaining a high index of suspicion when evaluating new or treatment-refractory skin lesions in patients with myeloproliferative neoplasms (MPNs), as early recognition may allow timely diagnosis of leukemic transformation and prompt initiation of appropriate therapy.

Indexed as

acute myeloid leukemiablastic phasedermatitisessential thrombocythemialeukemic infiltration

Identifiers

PMID41635379
PMCPMC12862877

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.