Evidence map›Paper›PMID 41635338›Full record

ArticleCureus2026

Syphilitic Uveitis-Associated Chiasmal Optic Neuritis Presenting As Bitemporal Hemianopia-Like Visual Field Defects.

Tomoya Ishibe, Mami Otsuka, Maho Itotani, Atsunobu Takeda

Abstract readCase Reports
In one paragraph

Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Tomoya IshibeDepartment of Ophthalmology, Oita University, Oita, JPN.
Mami OtsukaDepartment of Ophthalmology, Oita University, Oita, JPN.
Maho ItotaniDepartment of Ophthalmology, Oita University, Oita, JPN.
Atsunobu TakedaDepartment of Ophthalmology, Oita University, Oita, JPN.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Syphilis is a systemic infectious disease that can involve both ocular tissues and the central nervous system, with syphilitic uveitis representing one of its ocular manifestations. We report a rare case of syphilitic uveitis occurring in conjunction with chiasmal optic neuritis. A 48-year-old man presented with blurred vision in the right eye and was found to have bilateral acute syphilitic posterior placoid chorioretinitis with vitreous opacity in the left eye. Visual field testing demonstrated bitemporal hemianopia-like defects, and magnetic resonance imaging revealed enhancement of the optic chiasm. Serologic testing confirmed syphilis. Oral amoxicillin therapy resulted in complete resolution of the inflammation and recovery of vision. This case highlights that bitemporal hemianopia in patients with syphilitic uveitis may reflect concurrent chiasmal involvement rather than uveitic pathology alone, underscoring the importance of early diagnosis and appropriate treatment are crucial for achieving favorable visual outcomes.

Indexed as

acute syphilitic posterior placoid chorioretinitisbitemporal hemianopiachiasmal optic neuritisoral amoxicillin hydrate therapysyphilitic uveitis

Identifiers

PMID41635338
PMCPMC12862410

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.