ArticleCureus2026
Acquired Oral Hyperpigmentation: A Benign Finding or a Malignant Clue?
Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Laugier-Hunziker syndrome (LHS) is a rare, acquired pigmentary disorder characterized by mucocutaneous hyperpigmentation, primarily affecting the oral mucosa and nails. We present a case of a 76-year-old male patient with extensive melanotic macules on the oral mucosa, lips, tongue, genitalia, and acral regions. Histopathological examination revealed basal layer hyperpigmentation and dermal melanophages. Systemic involvement was excluded through interdisciplinary evaluation. LHS, though benign, requires differentiation from syndromes with malignant potential, such as Peutz-Jeghers syndrome. This case underscores the importance of recognizing LHS to avoid unnecessary interventions and ensure appropriate patient reassurance.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.