Evidence map›Paper›PMID 41635193›Full record

Trial reportInfection control and hospital epidemiology2026

Survey of hemodialysis patients' knowledge of their infection risk and acceptability of an intranasal decolonization intervention.

Fiona Armstrong-Pavlik, A M Racila, Melissa Ward, Rajeshwari Nair, Pam Tolomeo, Joseph Kellogg, Brenna Lindsey, Loreen A Herwaldt, Jesse T Jacob, Anitha Vijayan and 8 more

Registry-linked trialAbstract readRandomized Controlled TrialMulticenter Study
In one paragraph

Trial report in Infection control and hospital epidemiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04210505 (Povidone-iodine to Stop Access-related Infections and Transmission of Staphylococcus Aureus), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04210505 phase4active not recruitingnot on this map

Povidone-iodine to Stop Access-related Infections and Transmission of Staphylococcus Aureus (PAINTS)

TypeinterventionalSponsorMarin L. Schweizer, PhDRan2020 to 2024Enrolled302ConditionsStaphylococcus Aureus InfectionArmsPovidone-Iodine Topical Ointment, Standard Care
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Fiona Armstrong-PavlikUniversity of Iowa Carver College of Medicine, Iowa City, IA, USA.ORCID https://orcid.org/0000-0002-9922-5079
A M RacilaUniversity of Iowa Carver College of Medicine, Iowa City, IA, USA.ORCID https://orcid.org/0000-0002-5751-5422
Melissa WardUniversity of Iowa Carver College of Medicine, Iowa City, IA, USA.
Rajeshwari NairUniversity of Iowa Carver College of Medicine, Iowa City, IA, USA.
Pam TolomeoUniversity of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.
Joseph KelloggEmory University School of Medicine, Atlanta, GA, USA.
Brenna LindseyUniversity of Illinois at Chicago College of Medicine, Chicago, IL, USA.
Loreen A HerwaldtUniversity of Iowa Carver College of Medicine, Iowa City, IA, USA.
Jesse T JacobEmory University School of Medicine, Atlanta, GA, USA.
Anitha VijayanIntermountain Health, Salt Lake City, UT, USA.ORCID https://orcid.org/0000-0002-2128-1417
David PeguesUniversity of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.ORCID https://orcid.org/0000-0002-5295-0046
Jason CobbEmory University School of Medicine, Atlanta, GA, USA.
Mony FraerUniversity of Iowa Carver College of Medicine, Iowa City, IA, USA.
Susan B CaseyUniversity of Maryland Medical Center, Baltimore, MD, USA.ORCID https://orcid.org/0000-0001-7448-6259
Kimberly C DukesUniversity of Iowa Carver College of Medicine, Iowa City, IA, USA.ORCID https://orcid.org/0000-0001-6977-4221
Stacey Hockett SherlockUniversity of Iowa Carver College of Medicine, Iowa City, IA, USA.
Maryam HoppsDepartment of Medicine, School of Medicine and Public Health, University of Wisconsin-Madisonhttps://ror.org/01y2jtd41, Madison, WI, USA.
Marin Leigh SchweizerDepartment of Medicine, School of Medicine and Public Health, University of Wisconsin-Madisonhttps://ror.org/01y2jtd41, Madison, WI, USA.ORCID https://orcid.org/0000-0002-3604-0093

Funding

AHRQ HHS R01 HS026724
6 · The paper itself

Abstract

objectiveWhile infection is a leading cause of mortality among patients on hemodialysis, there are limited data on patients' infection prevention knowledge and attitudes. We aimed to assess hemodialysis patients' knowledge of their elevated infection risk, their willingness to actively prevent infections, and the acceptability of a long-term intranasal decolonization intervention.

designWe surveyed patients as part of a stepped wedge cluster randomized trial evaluating intranasal povidone-iodine (PVI) decolonization.

settingSixteen outpatient hemodialysis centers affiliated with 5 academic medical centers.

participantsPatients undergoing outpatient hemodialysis.

methodsPatients were asked to complete a pre-intervention survey (9 questions) and two intervention surveys (13 questions; only patients interested in PVI) at 1 month and 6 months after starting PVI. We used the chi-squared test to compare responses over time.

results469 (∼25%) participants completed at least one survey. Most (55%) participants underestimated their infection risk compared with an average person in the United States. The percentage of participants willing to expend "a lot of effort" to prevent an infection decreased from 79% (pre-intervention) to 63% (final survey) (

conclusionsPatients on hemodialysis underestimate their infection risk. Most patients found intranasal PVI to be acceptable. Future research should aim to improve patient education on their infection risk and remove barriers to adherence with infection prevention interventions.Clinical trial information: NCT04210505, https://clinicaltrials.gov/.

Indexed as

Anti-Infective Agents, LocalHealth Knowledge, Attitudes, PracticePovidone-IodineRenal DialysisAdministration, IntranasalAdultAgedFemaleHumansMaleMiddle AgedPatient Acceptance of Health CareSurveys and QuestionnairesAnti-Infective Agents, LocalPovidone-Iodine

Identifiers

PMID41635193
PMCPMC12875651

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.