Evidence map›Paper›PMID 41634999›Full record

ArticleJournal of neuroendocrinology2026

Determinants of incidence trends in pancreatic neuroendocrine neoplasms.

Giuseppe Lamberti, Elisa Andrini, Adriana Di Odoardo, Arianna Zappi, Claudio Ricci, Davide Campana

Abstract read
In one paragraph

Article in Journal of neuroendocrinology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Giuseppe LambertiDepartment of Medical and Surgical Sciences (DIMEC), University of Bologna, Bologna, Italy.ORCID https://orcid.org/0000-0003-3069-7630
Elisa AndriniDepartment of Medical and Surgical Sciences (DIMEC), University of Bologna, Bologna, Italy.
Adriana Di OdoardoDepartment of Medical and Surgical Sciences (DIMEC), University of Bologna, Bologna, Italy.ORCID https://orcid.org/0009-0003-0529-5274
Arianna ZappiDepartment of Medical and Surgical Sciences (DIMEC), University of Bologna, Bologna, Italy.
Claudio RicciDepartment of Medical and Surgical Sciences (DIMEC), University of Bologna, Bologna, Italy.
Davide CampanaDepartment of Medical and Surgical Sciences (DIMEC), University of Bologna, Bologna, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The incidence of pancreatic neuroendocrine neoplasms (NENs) is rising; whether this reflects a true increase in disease occurrence or improved detection remains uncertain. We conducted a retrospective, population-based study using data from the Surveillance, Epidemiology, and End Results (SEER) Program (1975-2021) to examine temporal trends in the incidence of pancreatic NENs and assess whether changes reflect improved detection versus a true increase. Incidence trends were stratified by demographic and socioeconomic proxies of healthcare access, including income, residential setting, and race as recorded in SEER at the county level. We identified 16,253 cases of pancreatic NENs (44.6% women; median age 62 years). Incidence increased 7.75-fold between 1975 and 2021, rising from 0.21 cases per 100,000 population in 1975 to 1.58 per 100,000 in 2021. Median tumour size at diagnosis decreased significantly, with an average annual reduction of 0.73 mm (R

Indexed as

Neuroendocrine TumorsPancreatic NeoplasmsAdultAgedFemaleHumansIncidenceMaleMiddle AgedRetrospective StudiesSEER ProgramUnited Stateshealthcare accessincidenceneuroendocrine neoplasmpancreasSEER

Identifiers

PMID41634999
PMCPMC12868397

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.