Evidence map›Paper›PMID 41634901›Full record

ArticleThe British journal of nutrition2026

Oral lactoferrin reduces systemic inflammation, enhances anti-viral responses and modulates immune cell profiles: a randomised controlled trial in healthy, older adults.

Bronwyn S Berthon, Evan J Williams, Lily M Williams, Kurtis F Budden, Sarah A Hiles, Nathan W Bartlett, Lisa G Wood

Abstract read
In one paragraph

Article in The British journal of nutrition, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Bronwyn S BerthonSchool of Biomedical Sciences and Pharmacy, https://ror.org/00eae9z71University of Newcastle, Callaghan, Australia.ORCID https://orcid.org/0000-0001-7858-6513
Evan J WilliamsSchool of Biomedical Sciences and Pharmacy, https://ror.org/00eae9z71University of Newcastle, Callaghan, Australia.
Lily M WilliamsSchool of Biomedical Sciences and Pharmacy, https://ror.org/00eae9z71University of Newcastle, Callaghan, Australia.
Kurtis F BuddenSchool of Biomedical Sciences and Pharmacy, https://ror.org/00eae9z71University of Newcastle, Callaghan, Australia.
Sarah A HilesSchool of Science, The University of Newcastle, Callaghan, Australia.
Nathan W BartlettSchool of Biomedical Sciences and Pharmacy, https://ror.org/00eae9z71University of Newcastle, Callaghan, Australia.
Lisa G WoodSchool of Biomedical Sciences and Pharmacy, https://ror.org/00eae9z71University of Newcastle, Callaghan, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This randomised controlled trial examined the effect of a 4-week, high-dose (Lf-High, 600 mg/d) or low-dose (Lf-Low, 200 mg/d) oral lactoferrin (Lf) intervention

Indexed as

immune functionLactoferrinrandomised controlled trialsystemic inflammation

Identifiers

PMID41634901
PMCPMC13315551

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.