Evidence map›Paper›PMID 41634820›Full record

ReviewJournal of cardiothoracic surgery2026

Clinical characteristics of 40 patients with spontaneous pneumomediastinum: a retrospective study and literature review.

Hui Tang, Jin Wang, Zhigang Qi, Jiabin Liu, Zhi Liu

Abstract readReview
In one paragraph

Review in Journal of cardiothoracic surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. When Asthma Leads to Air: Pneumomediastinum in a Child.Children (Basel, Switzerland) · 2026
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Hui Tang *Emergency Department, Xuanwu Hospital, Capital Medical University, National Clinical Research Center for Geriatric Diseases, No 45 Chang Chun Street, Xicheng District, 100053, Beijing, China. huitang@xwhosp.org.
Jin Wang *PhaseⅠClinical Trial Center, Beijing Ditan Hospital, Capital Medical University, Beijing, China.
Zhigang QiDiagnostic Radiology Division, Xuanwu Hospital, Capital Medical University, National Clinical Research Center for Geriatric Diseases, Beijing, China.
Jiabin LiuDiagnostic Radiology Division, Xuanwu Hospital, Capital Medical University, National Clinical Research Center for Geriatric Diseases, Beijing, China.
Zhi LiuEmergency Department, Xuanwu Hospital, Capital Medical University, National Clinical Research Center for Geriatric Diseases, No 45 Chang Chun Street, Xicheng District, 100053, Beijing, China.

Funding

National Key Research and Development Program Project: Establishing a Prevention and Control System for the Elderly Respiratory System 2020FYC2005402
6 · The paper itself

Abstract

objectiveTo investigate the clinical characteristics and imaging features of patients with spontaneous pneumomediastinum (SPM) and conduct a literature review to provide reference strategies for the diagnosis and treatment of the affected population.

methodsA retrospective analysis was conducted on patients diagnosed with SPM via chest computed tomography (CT) at our Hospital from January 2022 to December 2023. General information, clinical manifestations, and imaging findings were collected and analyzed. Relevant domestic and international literature was reviewed, and a comparative analysis was performed.

resultsA total of 40 patients were included in this study. Acute retrosternal pain was the most common symptom (45.0%), followed by varying degrees of dyspnea, shortness of breath, and chest tightness (25.0%), persistent coughing (17.5%), and discomfort or pain in the neck and throat (5%). The Macklin effect was observed in 38 patients, characterized by varying degrees of gas accumulation around the mediastinum near the pulmonary hilum. After three days of treatment, the symptoms resolved, and follow-up chest CT scans indicated absorption of mediastinal gas. Patients showed improvement and were discharged.

conclusionThe clinical manifestations of SPM are complex and diverse, making it prone to clinical misdiagnosis or delayed diagnosis, which may hinder timely treatment. Chest CT is instrumental in the accurate diagnosis of mild mediastinal emphysema. A comprehensive evaluation, incorporating patient complaints and clinical symptoms with chest CT findings, is essential for accurate diagnosis.

Indexed as

Mediastinal EmphysemaMediastinumAcute PainAdolescentAdultAgedAged, 80 and overChest PainCoughDyspneaFemaleHumansMaleMiddle AgedRetrospective StudiesTomography, X-Ray ComputedClinical characteristicsHigh-resolution chest computed tomographyLiterature reviewMacklin effectSpontaneous pneumomediastinum

Identifiers

PMID41634820
PMCPMC12955184

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.