Evidence map›Paper›PMID 41634751›Full record

ArticleMolecular brain2026

Impairment of novelty-dependent hippocampal behavioural tagging in Septin5-deficient mice.

Natsumi Ageta-Ishihara, Naoto Fukumasu, Kazuki Fujii, Yumie Koshidaka, Kenji Tanigaki, Takeshi Hiramoto, Gina Kang, Noboru Hiroi, Tsuyoshi Miyakawa, Keizo Takao and 1 more

Abstract read
In one paragraph

Article in Molecular brain, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Natsumi Ageta-IshiharaDepartment of Biomolecular Science, Faculty of Science, Toho University, 2-2-1 Miyama, Funabashi, Chiba, 274-8510, Japan. natsumi.ageta-ishihara@sci.toho-u.ac.jp.
Naoto FukumasuDepartment of Molecular Biology, Division of Biological Sciences, Nagoya University Graduate School of Science, Nagoya, Japan.
Kazuki FujiiDepartment of Behavioral Physiology, Faculty of Medicine, University of Toyama, Toyama, Japan.
Yumie KoshidakaLife Science Research Center, University of Toyama, Toyama, Japan.
Kenji TanigakiResearch Institute, Shiga Medical Center, Shiga, Japan.
Takeshi HiramotoDepartment of Pharmacology, University of Texas Health Science Center at San Antonio, San Antonio, USA.
Gina KangDepartment of Pharmacology, University of Texas Health Science Center at San Antonio, San Antonio, USA.
Noboru HiroiDepartment of Pharmacology, University of Texas Health Science Center at San Antonio, San Antonio, USA.
Tsuyoshi MiyakawaDivision of Systems Medical Science, Center for Medical Science, Fujita Health University, Aichi, Japan.
Keizo TakaoDepartment of Behavioral Physiology, Faculty of Medicine, University of Toyama, Toyama, Japan.
Makoto KinoshitaDepartment of Molecular Biology, Division of Biological Sciences, Nagoya University Graduate School of Science, Nagoya, Japan.

Funding

Postnatal mechanisms of cognitive development in miceR01MH099660 · NIMH · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI Noboru Hiroi · 2013 to 2026
$5.9M
Structure and Function of Neonatal Social Communication in Genetic Mouse Models of AutismR01DC015776 · NIDCD · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI HIROI, NOBORU · 2017 to 2021
$1.7M
22q11 Genes and Complex Behavior in MiceR21HD053114 · NICHD · ALBERT EINSTEIN COLLEGE OF MEDICINE · PI HIROI, NOBORU · 2008 to 2009
$453k
NICHD NIH HHS R21 HD053114NIDCD NIH HHS R01 DC015776NIMH NIH HHS R01 MH099660
6 · The paper itself

Abstract

Septin-5 is a GTP-binding protein implicated in synaptic vesicle exocytosis and 22q11.2 deletion-related neuropsychiatric disorders. We recently showed that Septin5-deficient (Septin5

Indexed as

Behavior, AnimalExploratory BehaviorHippocampusSeptinsAnimalsFearMaleMaze LearningMemoryMice, Inbred C57BLMice, KnockoutRecognition, PsychologySpatial MemorySept5 protein, mouseSeptinsBehavioural taggingHippocampusSeptin-5Septins

Identifiers

PMID41634751
PMCPMC12882602

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.