Evidence map›Paper›PMID 41634741›Full record

SynthesisBMC oral health2026

Artificial intelligence for binary dental caries diagnosis using intraoral images and dental radiographs: a systematic review and meta-analysis.

Jing Lai, Shanshan Guo, Ke Wang, Xulan Li, Xin Yu, Xueman Wang

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in BMC oral health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jing LaiChongqing Dental Hospital, No. 345 Minsheng Road, Yuzhong District, Chongqing, 400010, China.
Shanshan GuoChongqing Dental Hospital, No. 345 Minsheng Road, Yuzhong District, Chongqing, 400010, China.
Ke WangChongqing Dental Hospital, No. 345 Minsheng Road, Yuzhong District, Chongqing, 400010, China.
Xulan LiChongqing Dental Hospital, No. 345 Minsheng Road, Yuzhong District, Chongqing, 400010, China.
Xin YuChongqing Dental Hospital, No. 345 Minsheng Road, Yuzhong District, Chongqing, 400010, China.
Xueman WangChongqing Dental Hospital, No. 345 Minsheng Road, Yuzhong District, Chongqing, 400010, China. 771478334@qq.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesArtificial intelligence (AI) has shown increasing potential in dental diagnostics, yet its accuracy for binary classification of dental caries across different imaging modalities remains unclear. This study aimed to systematically evaluate the diagnostic performance of AI models using clinical intraoral images and dental radiographs.

methodsFollowing the PRISMA-DTA guidelines, PubMed, Embase, Scopus, Web of Science, and IEEE Xplore were systematically searched for studies published between January 2015 and June 2025. Eligible studies applied AI models for caries diagnosis with extractable sensitivity and specificity. Data on dentition, dataset, analysis unit, caries prevalence in test dataset, and preprocessing methods were extracted. Reporting quality and risk of bias were assessed using CLAIM and QUADAS-2. Pooled estimates were calculated with a bivariate random-effects model, with subgroup analyses by image type and analytical unit.

results25 studies met the criteria, and 13 were included in the meta-analysis. Pooled sensitivity, specificity, and the area under the curve (AUC) were 0.86, 0.91 and 0.94, respectively. Intraoral image-based models achieved higher sensitivity (0.88) and AUC (0.95), while radiograph-based models showed higher specificity (0.92). Tooth-level analyses yielded stable, clinically relevant performance (0.87/0.91). High heterogeneity (I² > 90%) was partly explained by image type, model architecture, reference standard variation, and test set caries prevalence.

conclusionAI models showed good diagnostic accuracy for caries detection across imaging modalities and analytical units. However, given the substantial heterogeneity and limitations in study quality and reference standards, these summary estimates should be interpreted with caution. AI-based systems may serve as complementary decision-support tools in clinical practice, but further standardization, external validation, and high-quality multicenter studies are required before broad clinical implementation.

Indexed as

Artificial IntelligenceDental CariesRadiography, DentalHumansSensitivity and SpecificityArtificial intelligenceDeep learningDental cariesDiagnostic accuracyMeta-analysisSystematic review

Identifiers

PMID41634741
PMCPMC12958653

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.