Evidence map›Paper›PMID 41634657›Full record

ArticleBMC health services research2026

Essential medicines out of reach: a cross-sectional study of community-level access in Eastern Uganda.

Samuel Baker Obakiro, Ronald Kibuuka, Brenda Nakazibwe, Andrew Marvin Kanyike, Francis Mawejje, Maureen Namugaya, Steven Nsereko Muwanga, Richard Maseruka, Catherine Nabitandikwa, Kenedy Kiyimba and 5 more

Abstract read
In one paragraph

Article in BMC health services research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Samuel Baker ObakiroDepartment of Pharmacology and Therapeutics, Faculty of Health Sciences, Busitema University, P.O. Box 1460, Mbale, Uganda.ORCID http://orcid.org/0000-0001-9258-2519
Ronald KibuukaDepartment of Pharmacology and Therapeutics, Faculty of Health Sciences, Busitema University, P.O. Box 1460, Mbale, Uganda. ronaldkibuuka1993@gmail.com.ORCID http://orcid.org/0009-0000-5265-4549
Brenda NakazibwePathogen Economy Bureau, Science, Technology and Innovation Secretariat - Office of the President P.O Box 7466, Kampala, Uganda.
Andrew Marvin KanyikeDepartment of Pharmacology and Therapeutics, Faculty of Health Sciences, Busitema University, P.O. Box 1460, Mbale, Uganda.ORCID http://orcid.org/0000-0002-8138-9083
Francis MawejjeDepartment of Pharmacology and Therapeutics, Faculty of Health Sciences, Busitema University, P.O. Box 1460, Mbale, Uganda.
Maureen NamugayaDepartment of Pharmacology and Therapeutics, Faculty of Health Sciences, Busitema University, P.O. Box 1460, Mbale, Uganda.
Steven Nsereko MuwangaDepartment of Pharmacology and Therapeutics, Faculty of Health Sciences, Busitema University, P.O. Box 1460, Mbale, Uganda.
Richard MaserukaDepartment of Pharmacology and Therapeutics, Faculty of Health Sciences, Busitema University, P.O. Box 1460, Mbale, Uganda.
Catherine NabitandikwaDepartment of Pharmacology and Therapeutics, Faculty of Health Sciences, Busitema University, P.O. Box 1460, Mbale, Uganda.ORCID http://orcid.org/0009-0007-9409-0471
Kenedy KiyimbaDepartment of Pharmacology and Therapeutics, Faculty of Health Sciences, Busitema University, P.O. Box 1460, Mbale, Uganda.ORCID http://orcid.org/0000-0001-8031-9051
Dan KibuuleDepartment of Pharmacology and Therapeutics, Faculty of Health Sciences, Busitema University, P.O. Box 1460, Mbale, Uganda.
Xinyang JiangVanke School of Public Health, Tsinghua University, Beijing, China.
Congzhou ChenVanke School of Public Health, Tsinghua University, Beijing, China.
Paul WaakoDepartment of Pharmacology and Therapeutics, Faculty of Health Sciences, Busitema University, P.O. Box 1460, Mbale, Uganda.
Guanqiao LiVanke School of Public Health, Tsinghua University, Beijing, China. guanqiaoli@tsinghua.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAccess to essential medicines is a critical indicator of a country’s commitment to public health, yet significant barriers persist in sub-Saharan Africa. In Eastern Uganda, most studies have focused on pharmaceutical supply chain-related factors that limit access to essential medicines, while community and patient-related factors, which are also major contributors, have been largely neglected.

objectiveTo assess the extent and determinants of access to essential medicines at the community level in Eastern Uganda, using a multidimensional WHO-aligned framework. METHODOLOGY: This was a household-based, cross-sectional survey conducted in the rural and urban communities of the Kibuku, Kapchorwa, and Mbale districts of Eastern Uganda, between February and April 2025. The household representatives were selected using multi-stage sampling. Access to essential medicines was defined using the five-point tool, comprising; availability, affordability, acceptability, accessibility, and accommodation/adequacy. Full access necessitated accomplishing all five criteria for the most recent episode of acute illness. Descriptive statistics were conducted to summarize participant characteristics, and bivariate and multivariable logistic regression to identify independent predictors of medicine access.

resultsOnly 8.55% of households reported access to essential medicines. Key challenges included frequent medicine stock-outs (72.52%) and high costs (68.92%). Participants engaged in informal employment were significantly less likely to access medicines (aOR: 0.24, 95% CI: 0.10–0.57, p = 0.001), as were those seeking care at public hospitals (aOR: 0.30, 95% CI: 0.11–0.86, p = 0.026) and households with a member living with a chronic disease (aOR: 0.37, 95% CI: 0.17–0.85, p = 0.019). Nearly half (44.03%) of the households had medicines stored at home including analgesics (39.6%), Antimalarials (20.6%), and Antibiotics (20.1%).

conclusionComprehensive access to essential medicine at the community level is critically low in Eastern Uganda. Addressing affordability, availability in public facilities, and support for households with chronic illness is critical in order to advance equity in medicine access.

Indexed as

Drugs, EssentialHealth Services AccessibilityAdultCross-Sectional StudiesFemaleHumansMaleMiddle AgedRural PopulationUgandaDrugs, EssentialAccessibilityAccommodationAffordabilityAvailabilityEssential medicinesHealth equitySociodemographic predictors

Identifiers

PMID41634657
PMCPMC12903647

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.