Evidence map›Paper›PMID 41634651›Full record

ArticleBMC women's health2026

Prevalence and associated factors of clinically significant symptoms of depression and anxiety among women with endometriosis in Iran.

Sarvenaz Emadi, Negin Fallahi-Khoshknab, Samira Abdollahi, Negar Emadi

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Article in BMC women's health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed
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1 · What the graph read from it

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3 · Its place in the literature

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1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Sarvenaz EmadiAlborz University of Medical Sciences, Karaj, Iran.
Negin Fallahi-KhoshknabUniversity of Social Welfare and Rehabilitation Sciences, Tehran, Iran. negfal@gmail.com.
Samira AbdollahiDepartment of Obstetrics and Gynecology, School of Medicine, Alborz University of Medical Sciences, Karaj, Iran. samiraabdollahi66@yahoo.com.
Negar EmadiBSc Biotechnology, Roudehen Branch, Islamic Azad University, Roudehen, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEndometriosis is a prevalent chronic condition that causes persistent pelvic pain, significantly impairing quality of life and contributing to psychological distress. This study aimed to assess the prevalence of clinically significant symptoms of depression and anxiety among women with endometriosis and to identify factors associated with these mental health outcomes.

methodsThis cross-sectional study was conducted between 2023 and 2024 at Shahid Kamali Hospital, Karaj, Iran. Women with a confirmed diagnosis of endometriosis by a gynecologist were recruited using convenience sampling. Participants completed the Hospital Anxiety and Depression Scale (HADS), a validated self-report screening tool, and clinical data were extracted from medical records. Univariate and multivariate logistic regression analyses were performed to identify demographic and clinical factors associated with clinically significant symptoms of depression and anxiety.

resultsA total of 112 women participated (mean age: 31.6 ± 4.9 years; mean BMI: 26.3 ± 3.7 kg/m²). The prevalence of clinically significant symptoms of depression and anxiety was 59.8% (95% CI: 50.4-68.6) and 54.5% (95% CI: 45.1-63.6), respectively. Univariate analyses showed that longer disease duration and higher pain intensity were significantly associated with depression, while education level was associated with anxiety. No significant association was found between endometriosis severity and either outcome. In the multivariate model, age, disease duration, and pain intensity remained significant correlates of depression, while education level and age were associated with anxiety.

conclusionsClinically significant symptoms of depression and anxiety were highly prevalent among women with endometriosis. Disease duration and pain intensity were the main factors associated with depressive symptoms, while education level was linked to anxiety. These findings emphasize the need for integrated physical and psychological care for women with endometriosis, particularly those experiencing prolonged disease and chronic pain.

Indexed as

AnxietyDepressionEndometriosisAdultCross-Sectional StudiesFemaleHumansIranPelvic PainPrevalenceQuality of LifeRisk FactorsAnxietyDepressionEndometriosisMental healthPain

Identifiers

PMID41634651
PMCPMC12918227

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