Evidence map›Paper›PMID 41634630›Full record

ArticleBMC public health2026

Long-term health outcomes and risk factors for low self-rated health in non-hospitalised adults with post-COVID-19 condition: a 2.5-year cohort study.

Anna Törnberg, Anna Svensson-Raskh, Elisabeth Rydwik, Annie Svensson, Mikael Björnsson, Daniel E Loewenstein, Michael Runold, Judith Bruchfeld, Malin Nygren-Bonnier

Abstract read
In one paragraph

Article in BMC public health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Anna TörnbergDivision of Physiotherapy, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, Huddinge, SE-141 83, Sweden. anna.tornberg@ki.se.ORCID http://orcid.org/0009-0008-8320-9948
Anna Svensson-RaskhDivision of Physiotherapy, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, Huddinge, SE-141 83, Sweden.ORCID http://orcid.org/0000-0002-7949-5864
Elisabeth RydwikDivision of Physiotherapy, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, Huddinge, SE-141 83, Sweden.ORCID http://orcid.org/0000-0003-0550-1675
Annie SvenssonDivision of Physiotherapy, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, Huddinge, SE-141 83, Sweden.ORCID http://orcid.org/0009-0006-7642-6157
Mikael BjörnssonDepartment of Medicine Solna, Karolinska Institutet, Stockholm, SE-171 76, Sweden.
Daniel E LoewensteinDepartment of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, SE-171 76, Sweden.ORCID http://orcid.org/0000-0003-2118-3056
Michael RunoldDepartment of Medicine Solna, Karolinska Institutet, Stockholm, SE-171 76, Sweden.
Judith BruchfeldDepartment of Medicine Solna, Karolinska Institutet, Stockholm, SE-171 76, Sweden.ORCID http://orcid.org/0000-0001-5399-0982
Malin Nygren-BonnierDivision of Physiotherapy, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, Huddinge, SE-141 83, Sweden.ORCID http://orcid.org/0000-0001-6731-8468

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundKnowledge regarding the clinical course and prognosis in non-hospitalised individuals with post-COVID-19 condition (PCC) remains limited. This study aimed to explore the impact of PCC on physical function, physical activity, and mental health in non-hospitalised adults, and to identify risk factors for low self-rated health. Extended knowledge may inform follow-up strategies and targeted interventions in non-hospitalised individuals with PCC.

methodsA cohort study was conducted at a specialised post-COVID clinic, with assessments of physical function (six-minute walk test, one-minute sit-to-stand test, maximal inspiratory pressure, mMRC dyspnoea), physical activity (Frändin/Grimby activity scale), mental health (depression: PHQ-9; anxiety: GAD-7), and self-rated health (EQ VAS) at 12 and 30 months after COVID-19. A total of 130 non-hospitalised adults with PCC were included. Data were collected between August 2020 and December 2024.

resultsParticipants were predominantly middle-aged, previously physically active women. Physical and mental impairments, and low physical activity remained prevalent at follow-up, despite some improvements over time. Impaired performance in the one-minute sit-to-stand test, a Frändin/Grimby activity level < 3, and a PHQ-9 score ≥ 10 at baseline were associated with lower EQ VAS scores at follow-up.

conclusionThere were long-term negative impacts of PCC on health outcomes 2.5 years after COVID-19 in non-hospitalised individuals, including impairments in physical and mental health, low physical activity, and low self-rated health. Impaired physical function, low physical activity, and depressive symptoms were identified as risk factors for low self-rated health. These findings expand current knowledge of prognosis in PCC, underscore the need for systematic follow-up using simple clinical tools to identify individuals at high risk, and inform targeted interventions to improve long-term outcomes.

Indexed as

COVID-19Health StatusAdultAgedCohort StudiesExerciseFemaleHumansMaleMental HealthMiddle AgedPost-Acute COVID-19 SyndromeRisk FactorsHealth-related quality of lifeMental healthPhysical activityPhysical fitnessPost-acute COVID-19 syndromeRecovery of function

Identifiers

PMID41634630
PMCPMC12930953

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.