Evidence map›Paper›PMID 41634586›Full record

ArticleBMC anesthesiology2026

Construction and evaluation of a PONV prediction model in patients undergoing orthopedic surgery under spinal anesthesia: a prospective cohort study.

Yuhua Zou, Ningkang Li, Cailan Li, Yanan Wu, Xiu Tang, Xiaoxue Sun, Qingshan Ye

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PubMed Full text at PMC Publisher
In one paragraph

Article in BMC anesthesiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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0cells of the map it votes in
1citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Yuhua Zou *Department of Anesthesiology, People's Hospital of Ningxia Hui Autonomous Region, Ningxia Medical University, 301 North Zhengyuan Street, Jinfeng District, Yinchuan City, Ningxia Hui Autonomous Region, 750001, China.
Ningkang Li *Department of Anesthesiology, People's Hospital of Ningxia Hui Autonomous Region, Ningxia Medical University, 301 North Zhengyuan Street, Jinfeng District, Yinchuan City, Ningxia Hui Autonomous Region, 750001, China.
Cailan LiDepartment of Anesthesiology, People's Hospital of Ningxia Hui Autonomous Region, Ningxia Medical University, 301 North Zhengyuan Street, Jinfeng District, Yinchuan City, Ningxia Hui Autonomous Region, 750001, China.
Yanan WuDepartment of Anesthesiology, People's Hospital of Ningxia Hui Autonomous Region, Ningxia Medical University, 301 North Zhengyuan Street, Jinfeng District, Yinchuan City, Ningxia Hui Autonomous Region, 750001, China.
Xiu TangDepartment of Anesthesiology, People's Hospital of Ningxia Hui Autonomous Region, Ningxia Medical University, 301 North Zhengyuan Street, Jinfeng District, Yinchuan City, Ningxia Hui Autonomous Region, 750001, China.
Xiaoxue SunDepartment of Anesthesiology, People's Hospital of Ningxia Hui Autonomous Region, Ningxia Medical University, 301 North Zhengyuan Street, Jinfeng District, Yinchuan City, Ningxia Hui Autonomous Region, 750001, China.
Qingshan YeDepartment of Anesthesiology, People's Hospital of Ningxia Hui Autonomous Region, Ningxia Medical University, 301 North Zhengyuan Street, Jinfeng District, Yinchuan City, Ningxia Hui Autonomous Region, 750001, China. yeqingshan@hotmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPostoperative nausea and vomiting (PONV) is a common complication following anesthesia. Most existing studies have focused on patients undergoing non-orthopedic surgeries with general anesthesia, neglecting the occurrence of PONV in patients receiving spinal anesthesia. This study aims to investigate the potential risk factors for PONV in patients undergoing orthopedic surgery with spinal anesthesia through a prospective cohort study and to construct and evaluate a clinical prediction model.

methodsRelevant factors associated with PONV in patients undergoing elective orthopedic surgery with spinal anesthesia from March11,2024, to October5,2024, were collected based on a literature review and clinical experience. Univariate and multivariate logistic regression analyses were conducted to identify potential predictive factors and construct a clinical prediction model. The model was evaluated using receiver operating characteristic (ROC) curves, calibration plots, and decision curve analysis (DCA), and was ultimately visualized using a nomogram.

resultsA total of 765 patients were ultimately included in this study, with a PONV incidence of 32.8% (251 cases). Multivariate logistic regression analysis revealed that female gender (OR = 2.51,95%CI:1.55–4.06, P < 0.001), a history of PONV (OR = 3.13,95% CI:1.73–5.67, P < 0.001), and preoperative pain scores (OR = 1.46,95% CI:1.08–1.98, P = 0.013) were independent predictive factors for PONV in patients undergoing orthopedic surgery with spinal anesthesia. Although non-smoking history, motion sickness history, preoperative high anxiety, and prolonged fasting did not demonstrate statistical significance, the study integrated these seven indicators based on clinical relevance to successfully construct a nomogram.

conclusionThe incidence of PONV is relatively high in patients undergoing orthopedic surgery with spinal anesthesia. Female gender, a history of PONV, and preoperative pain scores are identified as independent risk factors for the occurrence of PONV. The nomogram model constructed based on these factors demonstrates good predictive performance and clinical utility, aiding clinicians in the early identification of high-risk patients and the implementation of preventive strategies.

trial registrationThis study was registered on April 23, 2024, in the Chinese Clinical Trial Registry (Registration Number ChiCTR2400083373).This trial is retrospectively registered.

Indexed as

Anesthesia, SpinalOrthopedic ProceduresPostoperative Nausea and VomitingAdultAgedCohort StudiesFemaleHumansIncidenceMaleMiddle AgedNomogramsPrediction AlgorithmsProspective StudiesRisk FactorsNomogramOrthopedicsPONVPostoperative nausea and vomitingPrediction modelSpinal anesthesia

Identifiers

PMID41634586
PMCPMC12958769

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.