ArticleUpdates in surgery2026
Laparoscopic resection for gastric gastrointestinal stromal tumor at the esophagogastric junction: feasibility and long-term results.
Article in Updates in surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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6 authors.
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Abstract
BACKGROUND AND
aimDespite laparoscopic resection's established role in gastric gastrointestinal stromal tumor (GIST) management, its application for esophagogastric junction (EGJ) tumors involving the Z-line remains technically challenging and insufficiently studied. This study compares feasibility, safety, and oncologic outcomes of laparoscopic versus open resection for EGJ-GIST.
methodsA retrospective cohort analysis included 45 patients undergoing EGJ-GIST resection (24 laparoscopic, 21 open). Perioperative metrics and survival outcomes were evaluated, with clinicopathological parameters systematically compared.
resultsGroups had similar baseline characteristics. Laparoscopic surgery showed superior intraoperative outcomes, including reduced median blood loss (47.5 vs 85.0 mL, p < 0.001). Postoperatively, laparoscopic patients experienced faster gastrointestinal recovery (first flatus: 2 vs 3 days, p = 0.004), earlier dietary advancement (liquid: 3 vs 4 days, p = 0.003; solid: 4 vs 5 days, p < 0.001), and shorter hospitalization (6 vs 8 days, p = 0.002). Complication rates trended lower with laparoscopy (8.3% vs 23.8%, p = 0.306). Over 68-month median follow-up, recurrence occurred in 5 patients (laparoscopic:3; open:2). Five-year disease-free survival (DFS) (86.3% vs 87.7%) and overall survival (OS) (92.9% vs 93.3%) were comparable, with no intergroup differences in Kaplan-Meier analysis (DFS: p = 0.644; OS: p = 0.506). Multivariate analysis confirmed surgical approach did not independently affect prognosis.
conclusionsLaparoscopic resection for EGJ-GIST offers significant perioperative benefits-reduced blood loss, faster recovery, and fewer complications-while demonstrating comparable descriptive long-term survival rates to open surgery. These findings advocate prioritizing minimally invasive techniques in surgically selected cases.
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