ArticleJournal of medical systems2026
Deep Learning-based Assessment of Eyelid and Periorbital Parameters: Assisting Diagnosis and Treatment Planning in Blepharoptosis.
Article in Journal of medical systems, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Blepharoptosis is a common eyelid disorder that impairs both vision and appearance, requiring accurate assessment for effective treatment. This study aimed to develop and evaluate a deep learning (DL)-based system for automatic measurement of eyelid and periorbital parameters and for classifying levator function (LF) in patients with blepharoptosis. We retrospectively included 1,177 patients who underwent ptosis surgery at a tertiary oculoplastic center from January 2016 to November 2021. LF was categorized into good (> 10 mm), fair (4-10 mm), and poor (≤ 4 mm) based on clinical evaluation. The DL model segmented eyelid and eyebrow regions and measured key parameters; manual measurements were performed for comparison. A multinomial logistic regression model incorporating DL-derived features and demographic data was used to predict LF grades. The DL system achieved high segmentation performance (Dice coefficient = 0.910) and strong agreement with manual measurements (ICC = 0.988 for MRD1; 0.902 for CBH). The regression model classified LF grades with an overall accuracy of 0.760 and an AUC of 0.829, within the range of ophthalmologist assessments (highest clinician accuracy = 0.767). This DL-based system offers an efficient, objective tool for periorbital assessment and LF grading, supporting personalized diagnosis and surgical planning in blepharoptosis management.
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