Trial reportLasers in medical science2026
Effect of Bioptron light therapy on dryness of eyes in postmenopausal women: a randomized controlled trial.
Trial report in Lasers in medical science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05964673 (Effect of Bioptron Light Therapy on Dryness of Eyes in Postmenopausal Women), which is not on this map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Effect of Bioptron Light Therapy on Dryness of Eyes in Postmenopausal Women
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0 citing papers in PubMed.
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
To examine the short-term therapeutic effects of Bioptron light therapy (BLT) on dry eye disease (DED) in postmenopausal women. Sixty postmenopausal women diagnosed with DED, aged 50-62 years with a body mass index ≤ 30 kg/m², were randomly assigned to two equal groups. The Bioptron group (n = 30) received BLT for 10 min, twice weekly, along with an educational program for four weeks. The control group (n = 30) received the same educational program only. Outcomes were measured using Schirmer's test (Schirmer I) for basal tear secretion, Tear Break-Up Time (TBUT) for tear film stability, and the Dry Eye-related Quality of Life Score (DEQS) for quality of life (QOL). Both groups exhibited significant improvements post-treatment compared to pre-treatment in all variables, with greater percentage changes from baseline in the BLT group. Between-group comparisons revealed significantly higher improvements in the BLT group: Schirmer's test (Schirmer I) improved by MD = 8.7 (95% CI: 7.64-9.76; p = 0.001), TBUT by MD = 2.97 (95% CI: 1.7-4.3; p = 0.007), and DEQS decreased by MD = - 24.1 (95% CI: -37 to - 17.1; p = 0.002). Compared with standardized education alone, adjunctive Bioptron light therapy significantly enhanced tear secretion, tear film stability, and patient-reported symptoms, suggesting its potential as an effective non-pharmacological option for managing dry eye in postmenopausal women. The trial was registered at Clinical Trials.gov (Identifier: NCT05964673).
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