Evidence map›Paper›PMID 41634436›Full record

ArticleActa neurochirurgica2026

Reduced risk of shunt revision with adjustable valves: a population-based cohort study over three decades.

Siiri Oksa, Roosa Kasurinen, Anssi Lipponen, Ville Leinonen, Antti J Luikku

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Article in Acta neurochirurgica, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

5 authors.

Siiri OksaDepartment of Neurosurgery, Institute of Clinical Medicine, University of Eastern Finland, Kuopio, 70211, Finland. siioksa@uef.fi.
Roosa KasurinenDepartment of Neurosurgery, Institute of Clinical Medicine, University of Eastern Finland, Kuopio, 70211, Finland.
Anssi LipponenInstitute of Biomedicine, University of Eastern Finland, Kuopio, 70211, Finland.
Ville LeinonenDepartment of Neurosurgery, Institute of Clinical Medicine, University of Eastern Finland, Kuopio, 70211, Finland.
Antti J LuikkuDepartment of Neurosurgery, Institute of Clinical Medicine, University of Eastern Finland, Kuopio, 70211, Finland.

Funding

Alzheimer's Association ADSF-24-1284326-CKuopio University Hospital VTR Fund 5252614Research Council of Finland 339767
6 · The paper itself

Abstract

backgroundIdiopathic normal pressure hydrocephalus (iNPH) is a neurological disease characterized by ventriculomegaly and Hakim's triad. At present, symptoms can be alleviated only by cerebrospinal fluid (CSF) shunt surgery. Yet, various complications after shunting may occur, occasionally requiring repeated shunt revisions. In this retrospective, population-based study, our objective was to compare revision rates and causes for revision surgeries between adjustable shunt valve and fixed-pressure valves in iNPH patients.

methodsAltogether 1220 patients were evaluated for possible iNPH at Kuopio University Hospital between 1991 and 2023. Probable iNPH was diagnosed in 809 patients who received their first ventriculoperitoneal shunt (VPS). Of the patient cohort, 566 were shunted using an adjustable valve (2008-2023) and 243 received a fixed pressure valve (1991-2012). Hospital records and nationwide registries were used to construct a timeline for each patient from the shunt insertion and until death (n = 430) or the end of 2023.

resultsOverall revision rate was lower in iNPH patients receiving an adjustable valve (14% vs. 30%, p < .001, 95% CI 0.27-0.56). The incidence of multiple revisions was also lower in the adjustable valve group (27% vs. 32% p = 0.002, 95% CI 0.21-0.71). The most common cause for revision was peritoneal catheter malposition in the adjustable valve group (44%) and shunt underdrainage in the fixed-pressure valve group (25%).

conclusionsAdjustable shunt valves have decreased the need for shunt revision surgeries due to under- and overdrainage.

Indexed as

Cerebrospinal Fluid ShuntsHydrocephalus, Normal PressurePostoperative ComplicationsReoperationVentriculoperitoneal ShuntAgedAged, 80 and overCohort StudiesFemaleFinlandHumansMaleMiddle AgedRetrospective StudiesIdiopathic normal pressure hydrocephalusPrognosisRevision

Identifiers

PMID41634436
PMCPMC12872731

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