ArticleNature biomedical engineering2026
A programmable bioresorbable electrochemical microneedle sensor array for perioperative monitoring of organ health.
Article in Nature biomedical engineering, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
6 citing papers in PubMed.
- Hydrogel microneedles functioning in pathological surroundings: where soft materials overcome hard scars.Materials today. Bio · 2026Review
- Continuous Molecular Monitoring Using Electrochemical Aptamer-Based Sensors: Remaining Challenges for Long-Term In Vivo Deployment.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Review
- Bioelectronic Considerations in Biomedical Microneedles.Small (Weinheim an der Bergstrasse, Germany) · 2026Review
- Wearable Electronics for Precision Diagnosis Through Advanced Manufacturing and Integration.Nano-micro letters · 2026Review
- Bioresorbable electrochemical sensors for continuous deep-tissue lactate monitoring in critical care.Nature communications · 2026Article
- Evolution of 3D-Printed Microneedles toward Closed-Loop Theranostic Platforms.Research (Washington, D.C.) · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
Abstract
Comprehensive and continuous assessment of organ physiology and biochemistry, beyond the capabilities of conventional monitoring tools, can enable timely interventions for perioperative complications such as organ ischaemia and transplant rejection. Here we present an integrated bioresorbable system that enables multiplexed, real-time and spatially mapped electrochemical monitoring of deep organs throughout the surgical course. Using a 3D printing-based, photolithography-free fabrication process, the system features a flexible, 3D programmed, individually addressable microneedle sensor array with backward-facing barbs for conformal and stable organ interfacing and 3D parenchymal probing. Electrochemical functionalization of microneedle tips enable concurrent monitoring and spatial mapping of key biochemical markers, such as electrolytes, metabolites and oxygenation, in deep organs for at least 7 days. An electrically programmable self-destruction mechanism offers controllability over the degradation process, eliminating the need for device retrieval. Demonstrations in clinically relevant complications such as kidney ischaemia and gut disorders in animal models highlight the broad applications of this device in intra- and postoperative monitoring, advancing perioperative care and critical care medicine.
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.