Evidence map›Paper›PMID 41634386›Full record

ArticleBrazilian journal of microbiology : [publication of the Brazilian Society for Microbiology]2026

Genomic analysis of a multidrug-resistant monophasic Salmonella Typhimurium from Chinese beef harboring a novel mcr-1-bearing IncHI2-IncHI2A plasmid.

Xiaojuan Yang, Zekun Liu, Shixuan Huang, Shuzhen Cai, Ying Li, Liang Xue, Jumei Zhang, Qingping Wu

Abstract read
In one paragraph

Article in Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology], 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Xiaojuan YangState Key Laboratory of Applied Microbiology Southern China; National Health Commission Science and Technology Innovation Platform for Nutrition and Safety of Microbial Food; Guangdong Provincial Key Laboratory of Microbial Safety and Health; Institute of Microbiology, Guangdong Academy of Sciences, No. 100 Central Xianlie Road, Guangzhou, 510070, China. youngxj@126.com.ORCID http://orcid.org/0009-0007-7365-5234
Zekun LiuState Key Laboratory of Applied Microbiology Southern China; National Health Commission Science and Technology Innovation Platform for Nutrition and Safety of Microbial Food; Guangdong Provincial Key Laboratory of Microbial Safety and Health; Institute of Microbiology, Guangdong Academy of Sciences, No. 100 Central Xianlie Road, Guangzhou, 510070, China.
Shixuan HuangState Key Laboratory of Applied Microbiology Southern China; National Health Commission Science and Technology Innovation Platform for Nutrition and Safety of Microbial Food; Guangdong Provincial Key Laboratory of Microbial Safety and Health; Institute of Microbiology, Guangdong Academy of Sciences, No. 100 Central Xianlie Road, Guangzhou, 510070, China.
Shuzhen CaiState Key Laboratory of Applied Microbiology Southern China; National Health Commission Science and Technology Innovation Platform for Nutrition and Safety of Microbial Food; Guangdong Provincial Key Laboratory of Microbial Safety and Health; Institute of Microbiology, Guangdong Academy of Sciences, No. 100 Central Xianlie Road, Guangzhou, 510070, China.
Ying LiState Key Laboratory of Applied Microbiology Southern China; National Health Commission Science and Technology Innovation Platform for Nutrition and Safety of Microbial Food; Guangdong Provincial Key Laboratory of Microbial Safety and Health; Institute of Microbiology, Guangdong Academy of Sciences, No. 100 Central Xianlie Road, Guangzhou, 510070, China.
Liang XueState Key Laboratory of Applied Microbiology Southern China; National Health Commission Science and Technology Innovation Platform for Nutrition and Safety of Microbial Food; Guangdong Provincial Key Laboratory of Microbial Safety and Health; Institute of Microbiology, Guangdong Academy of Sciences, No. 100 Central Xianlie Road, Guangzhou, 510070, China.
Jumei ZhangState Key Laboratory of Applied Microbiology Southern China; National Health Commission Science and Technology Innovation Platform for Nutrition and Safety of Microbial Food; Guangdong Provincial Key Laboratory of Microbial Safety and Health; Institute of Microbiology, Guangdong Academy of Sciences, No. 100 Central Xianlie Road, Guangzhou, 510070, China.
Qingping WuState Key Laboratory of Applied Microbiology Southern China; National Health Commission Science and Technology Innovation Platform for Nutrition and Safety of Microbial Food; Guangdong Provincial Key Laboratory of Microbial Safety and Health; Institute of Microbiology, Guangdong Academy of Sciences, No. 100 Central Xianlie Road, Guangzhou, 510070, China. wuqp203@163.com.

Funding

Key Technologies Research and Development Program 2022YFF1100700
6 · The paper itself

Abstract

We conducted genomic analysis of a Chinese beef-derived, mcr-1-positive, multidrug-resistant monophasic Salmonella enterica serovar Typhimurium isolate. Antimicrobial resistance determinants were located on both its chromosome and plasmid. The multidrug resistance was primarily mediated by a novel IncHI2-IncHI2A plasmid harboring 18 resistance genes, including mcr-1, in contrast to only five resistance genes and one resistance-associated mutation detected on the chromosome. These findings underscore the need for enhanced surveillance of this pathogen.

Indexed as

Bacterial ProteinsDrug Resistance, Multiple, BacterialPlasmidsRed MeatSalmonella Infections, AnimalSalmonella typhimuriumAnimalsAnti-Bacterial AgentsCattleChinaGenome, BacterialGenomicsMicrobial Sensitivity TestsAnti-Bacterial AgentsBacterial Proteinsmcr-1Multidrug-resistantPlasmidSalmonella

Identifiers

PMID41634386
PMCPMC12868310

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.