Evidence map›Paper›PMID 41634339›Full record

ArticleScientific reports2026

Effect of simultaneous application of low-level diode laser and leukocyte platelet-rich fibrin on gingival tissue healing: an in vitro investigation.

Hamid Nazari, Mahshid Hodjat, Sogol Saberi, Faranak Noori, Sahar Hemmatian, Amir Raee

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Hamid NazariSchool of Dentistry, Tehran University of Medical Sciences, Tehran, Iran.
Mahshid HodjatDental Research Center, Dentistry Research Institute, Tehran University of Medical Sciences, Tehran, Iran.
Sogol SaberiLaser Research Center of Dentistry, Dentistry Research Institute, Tehran University of Medical Sciences, Tehran, Iran.
Faranak NooriDepartment of Endodontics, School of Dentistry, Tehran University of Medical Sciences, Tehran, Iran.
Sahar HemmatianDepartment of Periodontology, School of Dentistry, Tehran University of Medical Sciences, Tehran, Iran. Sahar.hemmatian@gmail.com.
Amir RaeeDepartment of Periodontology, School of Dentistry, Tehran University of Medical Sciences, Tehran, Iran. amirraee@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of the present in vitro study was to assess the simultaneous effect of low-level laser therapy (LLLT) and leucocyte platelet-rich fibrin (L-PRF) as adjunctive therapy on gingival tissue healing. Human gingival fibroblasts (HGFs) were cultured and subjected to different concentrations of L-PRF (100%, 50%, 25%, 12.5%, and 6.25%) and 915 nm diode laser with different energy densities (2, 3, and 4 J/cm

Indexed as

GingivaLasers, SemiconductorLeukocytesLow-Level Light TherapyPlatelet-Rich FibrinWound HealingCell MovementCell ProliferationCells, CulturedCell SurvivalCollagen Type ICollagen Type I, alpha 1 ChainFibroblastsHumansMatrix Metalloproteinase 1Collagen Type ICollagen Type I, alpha 1 ChainMatrix Metalloproteinase 1Guided tissue regenerationLow-level light therapyPeriodontal diseasesPhotobiomodulationPlatelet-rich fibrin

Identifiers

PMID41634339
PMCPMC12921302

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.