Evidence map›Paper›PMID 41634298›Full record

ArticleScientific reports2026

Development of a novel dismantlable adhesive for orthodontic use triggered by thermal stimulation.

Ayaka Shundo, Ko Nakanishi, Takayuki Kurokawa, Tomoo Kaneko, Kumiko Yoshihara, Aiko Matsumoto, Ryoshun Endo, Shuhei Otsubo, Takuya Fukuzoe, Tsukasa Akasaka and 3 more

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Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Ayaka ShundoDepartment of Orthodontics, Faculty of Dental Medicine, Hokkaido University, Kita 13, Nishi 7, Kita-ku, Sapporo, Hokkaido, 060-8586, Japan.
Ko NakanishiDepartment of Biomaterials and Bioengineering, Faculty of Dental Medicine, Hokkaido University, Kita 13, Nishi 7, Kita-ku, Sapporo, Hokkaido, 060-8586, Japan. nakanishi-ko@den.hokudai.ac.jp.
Takayuki KurokawaDepartment of Advanced Transdisciplinary Sciences, Faculty of Advanced Life Science, Hokkaido University, Kita 21, Nishi 11, Kita-ku, Sapporo, Hokkaido, 001-0021, Japan.
Tomoo KanekoCenter for Advanced Oral Medicine Clinic of Stomatognathic Function, Hokkaido University Hospital, Kita 14, Nishi 5, Sapporo, Hokkaido, 060-8648, Japan.
Kumiko YoshiharaHealth and Medical Research Institute, National Institute of Advanced Industrial Science and Technology, 2217-14 Hayashi-cho, Takamatsu, Kagawa, 761-0395, Japan.
Aiko MatsumotoDepartment of Orthodontics, Faculty of Dental Medicine, Hokkaido University, Kita 13, Nishi 7, Kita-ku, Sapporo, Hokkaido, 060-8586, Japan.
Ryoshun EndoDepartment of Orthodontics, Faculty of Dental Medicine, Hokkaido University, Kita 13, Nishi 7, Kita-ku, Sapporo, Hokkaido, 060-8586, Japan.
Shuhei OtsuboDepartment of Orthodontics, Faculty of Dental Medicine, Hokkaido University, Kita 13, Nishi 7, Kita-ku, Sapporo, Hokkaido, 060-8586, Japan.
Takuya FukuzoeDepartment of Orthodontics, Faculty of Dental Medicine, Hokkaido University, Kita 13, Nishi 7, Kita-ku, Sapporo, Hokkaido, 060-8586, Japan.
Tsukasa AkasakaDepartment of Biomaterials and Bioengineering, Faculty of Dental Medicine, Hokkaido University, Kita 13, Nishi 7, Kita-ku, Sapporo, Hokkaido, 060-8586, Japan.
Yasuhiro YoshidaDepartment of Biomaterials and Bioengineering, Faculty of Dental Medicine, Hokkaido University, Kita 13, Nishi 7, Kita-ku, Sapporo, Hokkaido, 060-8586, Japan.
Bart Van MeerbeekBIOMAT, Department of Oral Health Sciences, KULeuven & Dentistry, UZ Leuven, Kapucijnenvoer 7, 3000, Leuven, Belgium.
Yoshiaki SatoDepartment of Orthodontics, Faculty of Dental Medicine, Hokkaido University, Kita 13, Nishi 7, Kita-ku, Sapporo, Hokkaido, 060-8586, Japan.

Funding

Grants-in-Aid for Regional R&D Proposal-Based Program from Northern Advancement Center for Science & Technology of Hokkaido Japan T-1-30Japan Society for the Promotion of Science JP22K17222
6 · The paper itself

Abstract

This study aimed to develop a novel orthodontic adhesive material whose bond strength decreases under external stimuli for easy removal. Stearyl acrylate (SA) and methyl acrylate (MA) copolymerization gels with monomer ratios of 1:1 (SA/MA(1:1) gel) or 3:1 (SA/MA(3:1) gel) were synthesized and added to 4-methacryloxyethyl trimellitate anhydride/methyl methacrylate-tri-n-butyl borane resin (4META resin) at 30 wt% (4META resin-30% SA/MA(1:1) gel, 4META resin-30% SA/MA(3:1) gel). The thermal and mechanical properties of obtained adhesive were characterized. Bond strength was measured by shear testing at room temperature and at elevated temperatures (50 °C). Transition temperatures of 4META resin-30% SA/MA (1:1) gel and 4META resin-30% SA/MA (3:1) gel were 37.9 °C and 41.6 °C respectively from differential scanning calorimetry measurement. The shear strength of 4META resin, 4META resin-30%SA/MA(3:1) gel, and 4META resin-30%SA/MA(1:1) gel was 8.0 MPa, 8.4 MPa, and 7.1 MPa at room temperature and 6.0 MPa, 3.9 MPa, and 4.7 MPa at 50 °C. In 4META resin containing the copolymerized gel, Young's modulus and tensile strength, as well as shear strength, decreased significantly when the measurement temperature was set to 50 °C from room temperature. A novel adhesive that reduces bond strength by half or less upon temperature stimulation was successfully developed using SA and MA copolymer gels.

Indexed as

AdhesivesDental CementsAcrylatesCalorimetry, Differential ScanningMaterials TestingMethacrylatesShear StrengthTemperatureAcrylatesAdhesivesDental CementsMethacrylatesmethyl acrylateDismantlable adhesiveOrthodonticStearyl acrylate/methyl acrylate copolymer gelThermoresponsive polymer

Identifiers

PMID41634298
PMCPMC12920893

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.